``` In [2]: df = DataFrame({'a': [1,2,3], 'b': [1,2,3], 'c': [4,5,6]}) In [3]: df.set_index(['a','b'], inplace=True) Out[3]: c a b 1 1 4 2 2 5 3 3 6 In [5]: dropped = df.drop((1,1)) In [6]: dropped Out[6]: c 2 2 5 3 3 6 ``` MultiIndex is gone! (2,2) and (3,3) are now plain tuples