diff --git a/packages/create-instance/create-instance.js b/packages/create-instance/create-instance.js
index 1981dbe5c..918c2a85a 100644
--- a/packages/create-instance/create-instance.js
+++ b/packages/create-instance/create-instance.js
@@ -1,5 +1,6 @@
 // @flow
 
+import Vue from 'vue'
 import { createSlotVNodes } from './create-slot-vnodes'
 import addMocks from './add-mocks'
 import { addEventLogger } from './log-events'
@@ -109,10 +110,35 @@ export default function createInstance (
     component.options._base = _Vue
   }
 
+  function getRootVueProto (obj) {
+    while (obj) {
+      if (Object.getPrototypeOf(obj) === Vue.prototype) {
+        return obj
+      }
+
+      obj = Object.getPrototypeOf(obj)
+    }
+  }
+
+  function getExtendedComponent (component, instanceOptions) {
+    // extend _Vue to merge the mixins on _Vue
+    const extendedComponent = component.extend(_Vue).extend(instanceOptions)
+
+    // cache subclass constructor
+    component.options._Ctor[extendedComponent.cid] = extendedComponent
+
+    // to keep the possible overridden prototype and _Vue mocks on prototype,
+    // we need change the proto chains manually
+    // @see https://github.com/vuejs/vue-test-utils/pull/856
+    const root = getRootVueProto(extendedComponent.prototype)
+    Object.setPrototypeOf(root, _Vue.prototype)
+
+    return extendedComponent
+  }
+
   // extend component from _Vue to add properties and mixins
-  // extend does not work correctly for sub class components in Vue < 2.2
-  const Constructor = typeof component === 'function' && vueVersion < 2.3
-    ? component.extend(instanceOptions)
+  const Constructor = typeof component === 'function'
+    ? getExtendedComponent(component, instanceOptions)
     : _Vue.extend(component).extend(instanceOptions)
 
   // Keep reference to component mount was called with
diff --git a/test/specs/mount.spec.js b/test/specs/mount.spec.js
index e5ab2c6cd..20127b822 100644
--- a/test/specs/mount.spec.js
+++ b/test/specs/mount.spec.js
@@ -156,27 +156,29 @@ describeRunIf(process.env.TEST_ENV !== 'node', 'mount', () => {
       expect(stub).not.called
     })
 
-  it.skip('overrides component prototype', () => {
-    const mountSpy = sinon.spy()
-    const destroySpy = sinon.spy()
-    const Component = Vue.extend({})
-    const { $mount: originalMount, $destroy: originalDestroy } = Component.prototype
-    Component.prototype.$mount = function (...args) {
-      originalMount.apply(this, args)
-      mountSpy()
-      return this
-    }
-    Component.prototype.$destroy = function () {
-      originalDestroy.apply(this)
-      destroySpy()
-    }
+  itDoNotRunIf(
+    vueVersion < 2.3,
+    'overrides component prototype', () => {
+      const mountSpy = sinon.spy()
+      const destroySpy = sinon.spy()
+      const Component = Vue.extend({})
+      const { $mount: originalMount, $destroy: originalDestroy } = Component.prototype
+      Component.prototype.$mount = function (...args) {
+        originalMount.apply(this, args)
+        mountSpy()
+        return this
+      }
+      Component.prototype.$destroy = function () {
+        originalDestroy.apply(this)
+        destroySpy()
+      }
 
-    const wrapper = mount(Component)
-    expect(mountSpy).called
-    expect(destroySpy).not.called
-    wrapper.destroy()
-    expect(destroySpy).called
-  })
+      const wrapper = mount(Component)
+      expect(mountSpy).called
+      expect(destroySpy).not.called
+      wrapper.destroy()
+      expect(destroySpy).called
+    })
 
   // Problems accessing options of twice extended components in Vue < 2.3
   itDoNotRunIf(vueVersion < 2.3, 'compiles extended components', () => {