diff --git a/compiler/src/dotty/tools/dotc/ast/tpd.scala b/compiler/src/dotty/tools/dotc/ast/tpd.scala
index b9a6edcc6bc3..964f50ceb18d 100644
--- a/compiler/src/dotty/tools/dotc/ast/tpd.scala
+++ b/compiler/src/dotty/tools/dotc/ast/tpd.scala
@@ -5,6 +5,7 @@ package ast
 import dotty.tools.dotc.transform.{ExplicitOuter, Erasure}
 import dotty.tools.dotc.typer.ProtoTypes.FunProtoTyped
 import transform.SymUtils._
+import transform.TypeUtils._
 import core._
 import util.Positions._, Types._, Contexts._, Constants._, Names._, Flags._, NameOps._
 import SymDenotations._, Symbols._, StdNames._, Annotations._, Trees._, Symbols._
@@ -377,7 +378,7 @@ object tpd extends Trees.Instance[Type] with TypedTreeInfo {
   }
 
   /** A tree representing a `newXYZArray` operation of the right
-   *  kind for the given element type in `typeArg`. No type arguments or
+   *  kind for the given element type in `elemTpe`. No type arguments or
    *  `length` arguments are given.
    */
   def newArray(elemTpe: Type, returnTpe: Type, pos: Position, dims: JavaSeqLiteral)(implicit ctx: Context): Tree = {
@@ -392,6 +393,32 @@ object tpd extends Trees.Instance[Type] with TypedTreeInfo {
       newArr.appliedToArgs(clsOf(elemTpe) :: clsOf(returnTpe) :: dims :: Nil).withPos(pos)
   }
 
+  /** The wrapped array method name for an array of type elemtp */
+  def wrapArrayMethodName(elemtp: Type)(implicit ctx: Context): TermName = {
+    val elemCls = elemtp.classSymbol
+    if (elemCls.isPrimitiveValueClass) nme.wrapXArray(elemCls.name)
+    else if (elemCls.derivesFrom(defn.ObjectClass) && !elemCls.isNotRuntimeClass) nme.wrapRefArray
+    else nme.genericWrapArray
+  }
+
+  /** A tree representing a `wrapXYZArray(tree)` operation of the right
+   *  kind for the given element type in `elemTpe`.
+   */
+  def wrapArray(tree: Tree, elemtp: Type)(implicit ctx: Context): Tree = {
+    val wrapped = ref(defn.ScalaPredefModule)
+      .select(wrapArrayMethodName(elemtp))
+      .appliedToTypes(if (elemtp.isPrimitiveValueType) Nil else elemtp :: Nil)
+      .appliedTo(tree)
+
+    if (ctx.settings.YimmutableSeq.value) {
+      // wrapXYZArray returns a `mutable.Seq`. We need to convert to a `immutable.Seq`.
+      // TODO: revert once we use the 2.13 standard library and have better
+      // collections for immutable wrapped arrays (i.e. immutbale.ArraySeq)
+      wrapped.select(nme.toList)
+    }
+    else wrapped
+  }
+
   // ------ Creating typed equivalents of trees that exist only in untyped form -------
 
   /** new C(args), calling the primary constructor of C */
diff --git a/compiler/src/dotty/tools/dotc/config/ScalaSettings.scala b/compiler/src/dotty/tools/dotc/config/ScalaSettings.scala
index dfda54f034e7..27086d3f1c86 100644
--- a/compiler/src/dotty/tools/dotc/config/ScalaSettings.scala
+++ b/compiler/src/dotty/tools/dotc/config/ScalaSettings.scala
@@ -124,6 +124,7 @@ class ScalaSettings extends Settings.SettingGroup {
   val YcheckAllPatmat = BooleanSetting("-Ycheck-all-patmat", "Check exhaustivity and redundancy of all pattern matching (used for testing the algorithm)")
   val YretainTrees = BooleanSetting("-Yretain-trees", "Retain trees for top-level classes, accessible from ClassSymbol#tree")
   val YshowTreeIds = BooleanSetting("-Yshow-tree-ids", "Uniquely tag all tree nodes in debugging output.")
+  val YimmutableSeq = BooleanSetting("-Yimmutable-seq", "Use collection.immutable.Seq as the default Seq type")
 
   val YprofileEnabled = BooleanSetting("-Yprofile-enabled", "Enable profiling.")
   val YprofileDestination = StringSetting("-Yprofile-destination", "file", "where to send profiling output - specify a file, default is to the console.", "")
diff --git a/compiler/src/dotty/tools/dotc/core/Definitions.scala b/compiler/src/dotty/tools/dotc/core/Definitions.scala
index 18f46407ddd8..e8f98d5a78d7 100644
--- a/compiler/src/dotty/tools/dotc/core/Definitions.scala
+++ b/compiler/src/dotty/tools/dotc/core/Definitions.scala
@@ -9,7 +9,6 @@ import scala.collection.{ mutable, immutable }
 import PartialFunction._
 import collection.mutable
 import util.common.alwaysZero
-import dotty.tools.dotc.transform.TreeGen
 
 object Definitions {
 
@@ -347,7 +346,7 @@ class Definitions {
     def Predef_undefined(implicit ctx: Context) = Predef_undefinedR.symbol
     // The set of all wrap{X, Ref}Array methods, where X is a value type
     val Predef_wrapArray = new PerRun[collection.Set[Symbol]]({ implicit ctx =>
-      val methodNames = ScalaValueTypes.map(TreeGen.wrapArrayMethodName) + nme.wrapRefArray
+      val methodNames = ScalaValueTypes.map(ast.tpd.wrapArrayMethodName) + nme.wrapRefArray
       methodNames.map(ScalaPredefModule.requiredMethodRef(_).symbol)
     })
 
@@ -401,7 +400,12 @@ class Definitions {
       List(AnyClass.typeRef), EmptyScope)
   lazy val SingletonType: TypeRef = SingletonClass.typeRef
 
-  lazy val SeqType: TypeRef = ctx.requiredClassRef("scala.collection.Seq")
+  lazy val SeqType: TypeRef = {
+    val fullName =
+      if (ctx.settings.YimmutableSeq.value) "scala.collection.immutable.Seq"
+      else "scala.collection.Seq"
+    ctx.requiredClassRef(fullName)
+  }
   def SeqClass(implicit ctx: Context) = SeqType.symbol.asClass
     lazy val Seq_applyR = SeqClass.requiredMethodRef(nme.apply)
     def Seq_apply(implicit ctx: Context) = Seq_applyR.symbol
diff --git a/compiler/src/dotty/tools/dotc/transform/ElimRepeated.scala b/compiler/src/dotty/tools/dotc/transform/ElimRepeated.scala
index 23b6dfb4dd5e..12ca02ac1439 100644
--- a/compiler/src/dotty/tools/dotc/transform/ElimRepeated.scala
+++ b/compiler/src/dotty/tools/dotc/transform/ElimRepeated.scala
@@ -143,7 +143,7 @@ class ElimRepeated extends MiniPhase with InfoTransformer { thisPhase =>
       val elemtp = varArgRef.tpe.widen.argTypes.head
       ref(original.termRef)
         .appliedToTypes(trefs)
-        .appliedToArgs(vrefs :+ TreeGen.wrapArray(varArgRef, elemtp))
+        .appliedToArgs(vrefs :+ tpd.wrapArray(varArgRef, elemtp))
         .appliedToArgss(vrefss1)
     })
 
diff --git a/compiler/src/dotty/tools/dotc/transform/SeqLiterals.scala b/compiler/src/dotty/tools/dotc/transform/SeqLiterals.scala
index 756e4f045cb6..2e17a211a04d 100644
--- a/compiler/src/dotty/tools/dotc/transform/SeqLiterals.scala
+++ b/compiler/src/dotty/tools/dotc/transform/SeqLiterals.scala
@@ -35,14 +35,6 @@ class SeqLiterals extends MiniPhase {
       val arr = JavaSeqLiteral(tree.elems, tree.elemtpt)
       //println(i"trans seq $tree, arr = $arr: ${arr.tpe} ${arr.tpe.elemType}")
       val elemtp = tree.elemtpt.tpe
-      val elemCls = elemtp.classSymbol
-      val (wrapMethStr, targs) =
-        if (elemCls.isPrimitiveValueClass) (s"wrap${elemCls.name}Array", Nil)
-        else if (elemtp derivesFrom defn.ObjectClass) ("wrapRefArray", elemtp :: Nil)
-        else ("genericWrapArray", elemtp :: Nil)
-      ref(defn.ScalaPredefModule)
-        .select(wrapMethStr.toTermName)
-        .appliedToTypes(targs)
-        .appliedTo(arr)
+      wrapArray(arr, elemtp)
   }
 }
diff --git a/compiler/src/dotty/tools/dotc/transform/TreeGen.scala b/compiler/src/dotty/tools/dotc/transform/TreeGen.scala
deleted file mode 100644
index a6dfdebc3cf4..000000000000
--- a/compiler/src/dotty/tools/dotc/transform/TreeGen.scala
+++ /dev/null
@@ -1,26 +0,0 @@
-package dotty.tools.dotc
-package transform
-
-import core._
-import Symbols._, Contexts._, Types._, Names._, StdNames._
-import ast._
-import Trees._
-import TypeUtils._
-
-object TreeGen {
-
-  import tpd._
-
-  def wrapArrayMethodName(elemtp: Type)(implicit ctx: Context): TermName = {
-    val elemCls = elemtp.classSymbol
-    if (elemCls.isPrimitiveValueClass) nme.wrapXArray(elemCls.name)
-    else if (elemCls.derivesFrom(defn.ObjectClass) && !elemCls.isNotRuntimeClass) nme.wrapRefArray
-    else nme.genericWrapArray
-  }
-
-  def wrapArray(tree: Tree, elemtp: Type)(implicit ctx: Context): Tree =
-    ref(defn.ScalaPredefModule)
-      .select(wrapArrayMethodName(elemtp))
-      .appliedToTypes(if (elemtp.isPrimitiveValueType) Nil else elemtp :: Nil)
-      .appliedTo(tree)
-}
diff --git a/compiler/src/dotty/tools/dotc/typer/Implicits.scala b/compiler/src/dotty/tools/dotc/typer/Implicits.scala
index 848d928d7cf5..4ba82bc897b9 100644
--- a/compiler/src/dotty/tools/dotc/typer/Implicits.scala
+++ b/compiler/src/dotty/tools/dotc/typer/Implicits.scala
@@ -71,7 +71,7 @@ object Implicits {
     /** The implicit references */
     def refs: List[ImplicitRef]
 
-    private var SingletonClass: ClassSymbol = null
+    private[this] var SingletonClass: ClassSymbol = null
 
     /** Widen type so that it is neither a singleton type nor a type that inherits from scala.Singleton. */
     private def widenSingleton(tp: Type)(implicit ctx: Context): Type = {
diff --git a/compiler/test/dotty/tools/dotc/CompilationTests.scala b/compiler/test/dotty/tools/dotc/CompilationTests.scala
index e0b81251ed29..dee3defaba28 100644
--- a/compiler/test/dotty/tools/dotc/CompilationTests.scala
+++ b/compiler/test/dotty/tools/dotc/CompilationTests.scala
@@ -58,6 +58,7 @@ class CompilationTests extends ParallelTesting {
     compileFile("tests/pos-special/completeFromSource/Test.scala", defaultOptions.and("-sourcepath", "tests/pos-special")) +
     compileFile("tests/pos-special/completeFromSource/Test2.scala", defaultOptions.and("-sourcepath", "tests/pos-special")) +
     compileFile("tests/pos-special/completeFromSource/Test3.scala", defaultOptions.and("-sourcepath", "tests/pos-special", "-scansource")) +
+    compileFile("tests/pos-special/repeatedArgs.scala", defaultOptions.and("-Yimmutable-seq")) +
     compileFilesInDir("tests/pos-special/fatal-warnings", defaultOptions.and("-Xfatal-warnings")) +
     compileList(
       "compileMixed",
@@ -189,8 +190,9 @@ class CompilationTests extends ParallelTesting {
     compileFile("tests/neg-custom-args/i3882.scala", allowDeepSubtypes) +
     compileFile("tests/neg-custom-args/i4372.scala", allowDeepSubtypes) +
     compileFile("tests/neg-custom-args/i1754.scala", allowDeepSubtypes) +
-    compileFilesInDir("tests/neg-custom-args/isInstanceOf", allowDeepSubtypes and "-Xfatal-warnings") +
-    compileFile("tests/neg-custom-args/i3627.scala", allowDeepSubtypes)
+    compileFile("tests/neg-custom-args/i3627.scala", allowDeepSubtypes) +
+    compileFile("tests/neg-custom-args/repeatedArgs.scala", defaultOptions.and("-Yimmutable-seq")) +
+    compileFilesInDir("tests/neg-custom-args/isInstanceOf", allowDeepSubtypes and "-Xfatal-warnings")
   }.checkExpectedErrors()
 
   // Run tests -----------------------------------------------------------------
diff --git a/tests/neg-custom-args/repeatedArgs.scala b/tests/neg-custom-args/repeatedArgs.scala
new file mode 100644
index 000000000000..8c20a3ae7b86
--- /dev/null
+++ b/tests/neg-custom-args/repeatedArgs.scala
@@ -0,0 +1,19 @@
+import scala.collection.{immutable, mutable}
+import java.nio.file.Paths
+
+/** Compiled with `-Yimmutable-seq` */
+class repeatedArgs {
+  def bar(xs: String*): Int = xs.length
+
+  def test(xs: immutable.Seq[String], ys: collection.Seq[String], zs: Array[String]): Unit = {
+    bar("a", "b", "c")
+    bar(xs: _*)
+    bar(ys: _*) // error: immutable.Seq expected, found Seq
+    bar(zs: _*) // error: immutable.Seq expected, found Array
+
+    Paths.get("Hello", "World")
+    Paths.get("Hello", xs: _*)
+    Paths.get("Hello", ys: _*) // error: immutable.Seq expected, found Seq
+    Paths.get("Hello", zs: _*) // error: immutable.Seq expected, found Array
+  }
+}
diff --git a/tests/pos-special/repeatedArgs.scala b/tests/pos-special/repeatedArgs.scala
new file mode 100644
index 000000000000..1db5ad0acfd9
--- /dev/null
+++ b/tests/pos-special/repeatedArgs.scala
@@ -0,0 +1,18 @@
+import scala.collection.{immutable, mutable}
+import java.nio.file.Paths
+
+/** Compiled with `-Yimmutable-seq` */
+class repeatedArgs {
+  def bar(xs: String*): Int = xs.length
+
+  def test(xs: immutable.Seq[String]): Unit = {
+    bar("a", "b", "c")
+    bar(xs: _*)
+
+    Paths.get("Hello", "World")
+    Paths.get("Hello", xs: _*)
+
+    val List(_, others: _*) = xs.toList // toList should not be needed, see #4790
+    val x: immutable.Seq[String] = others
+  }
+}
diff --git a/tests/pos/repeatedArgs.scala b/tests/pos/repeatedArgs.scala
index f9abb4aee70e..4bd51e5a15ef 100644
--- a/tests/pos/repeatedArgs.scala
+++ b/tests/pos/repeatedArgs.scala
@@ -1,3 +1,22 @@
-object testRepeated {
- def foo = java.lang.System.out.format("%4$2s %3$2s %2$2s %1$2s", "a", "b", "c", "d")
+import scala.collection.{immutable, mutable}
+import java.nio.file.Paths
+
+class repeatedArgs {
+  def bar(xs: String*): Int = xs.length
+
+  def test(xs: immutable.Seq[String], ys: collection.Seq[String], zs: Array[String]): Unit = {
+    bar("a", "b", "c")
+    bar(xs: _*)
+    bar(ys: _*) // error in 2.13
+    bar(zs: _*)
+
+    Paths.get("Hello", "World")
+    Paths.get("Hello", xs: _*)
+    Paths.get("Hello", ys: _*) // error in 2.13
+    Paths.get("Hello", zs: _*)
+
+    val List(_, others: _*) = xs.toList // toList should not be needed, see #4790
+    val x: collection.Seq[String] = others
+    // val y: immutable.Seq[String] = others // ok in 2.13
+  }
 }