diff --git a/compiler/rustc_typeck/src/astconv/mod.rs b/compiler/rustc_typeck/src/astconv/mod.rs
index 8a5c7fee697d1..c094594648cbf 100644
--- a/compiler/rustc_typeck/src/astconv/mod.rs
+++ b/compiler/rustc_typeck/src/astconv/mod.rs
@@ -2667,7 +2667,10 @@ impl<'o, 'tcx> dyn AstConv<'tcx> + 'o {
                 self.normalize_ty(ast_ty.span, array_ty)
             }
             hir::TyKind::Typeof(ref e) => {
-                let ty = tcx.type_of(tcx.hir().local_def_id(e.hir_id));
+                let ty_erased = tcx.type_of(tcx.hir().local_def_id(e.hir_id));
+                let ty = tcx.fold_regions(ty_erased, |r, _| {
+                    if r.is_erased() { tcx.lifetimes.re_static } else { r }
+                });
                 let span = ast_ty.span;
                 tcx.sess.emit_err(TypeofReservedKeywordUsed {
                     span,
diff --git a/src/test/ui/typeof/issue-100183.rs b/src/test/ui/typeof/issue-100183.rs
new file mode 100644
index 0000000000000..13e9493eaa59b
--- /dev/null
+++ b/src/test/ui/typeof/issue-100183.rs
@@ -0,0 +1,6 @@
+struct Struct {
+    y: (typeof("hey"),),
+    //~^ ERROR `typeof` is a reserved keyword but unimplemented
+}
+
+fn main() {}
diff --git a/src/test/ui/typeof/issue-100183.stderr b/src/test/ui/typeof/issue-100183.stderr
new file mode 100644
index 0000000000000..01d3079b246d1
--- /dev/null
+++ b/src/test/ui/typeof/issue-100183.stderr
@@ -0,0 +1,14 @@
+error[E0516]: `typeof` is a reserved keyword but unimplemented
+  --> $DIR/issue-100183.rs:2:9
+   |
+LL |     y: (typeof("hey"),),
+   |         ^^^^^^^^^^^^^ reserved keyword
+   |
+help: consider replacing `typeof(...)` with an actual type
+   |
+LL |     y: (&'static str,),
+   |         ~~~~~~~~~~~~
+
+error: aborting due to previous error
+
+For more information about this error, try `rustc --explain E0516`.