diff --git a/pytensor/tensor/variable.py b/pytensor/tensor/variable.py
index bad700de8b..7e5d22528a 100644
--- a/pytensor/tensor/variable.py
+++ b/pytensor/tensor/variable.py
@@ -346,7 +346,7 @@ def dimshuffle(self, *pattern):
         DimShuffle
 
         """
-        if (len(pattern) == 1) and (isinstance(pattern[0], list | tuple)):
+        if (len(pattern) == 1) and (isinstance(pattern[0], list | tuple | np.ndarray)):
             pattern = pattern[0]
         ds_op = pt.elemwise.DimShuffle(input_ndim=self.type.ndim, new_order=pattern)
         return ds_op(self)
diff --git a/tests/tensor/test_variable.py b/tests/tensor/test_variable.py
index 57e47ce064..2c6f818c30 100644
--- a/tests/tensor/test_variable.py
+++ b/tests/tensor/test_variable.py
@@ -451,6 +451,21 @@ def test_set_item_error(self):
         with pytest.raises(TypeError, match=msg):
             x[0] += 5
 
+    def test_transpose(self):
+        X, _ = self.vars
+        x, _ = self.vals
+
+        # Turn (2,2) -> (1,2)
+        X, x = X[1:, :], x[1:, :]
+
+        assert_array_equal(X.transpose(0, 1).eval({X: x}), x.transpose(0, 1))
+        assert_array_equal(X.transpose(1, 0).eval({X: x}), x.transpose(1, 0))
+
+        # Test handing in tuples, lists and np.arrays
+        equal_computations([X.transpose((1, 0))], [X.transpose(1, 0)])
+        equal_computations([X.transpose([1, 0])], [X.transpose(1, 0)])
+        equal_computations([X.transpose(np.array([1, 0]))], [X.transpose(1, 0)])
+
 
 def test_deprecated_import():
     with pytest.warns(