diff --git a/packages/javascript/jupyterlab-plotly/src/Figure.ts b/packages/javascript/jupyterlab-plotly/src/Figure.ts
index 05403546974..6b0b4a63342 100644
--- a/packages/javascript/jupyterlab-plotly/src/Figure.ts
+++ b/packages/javascript/jupyterlab-plotly/src/Figure.ts
@@ -826,11 +826,9 @@ export class FigureView extends DOMWidgetView {
     this.model.on("change:_py2js_update", this.do_update, this);
     this.model.on("change:_py2js_animate", this.do_animate, this);
 
-    // MathJax configuration
+    // MathJax v2 configuration
     // ---------------------
-    if ((window as any).MathJax) {
-      (window as any).MathJax.Hub.Config({ SVG: { font: "STIX-Web" } });
-    }
+    (window as any)?.MathJax?.Hub?.Config?.({ SVG: { font: "STIX-Web" } });
 
     // Get message ids
     // ---------------------
diff --git a/packages/python/plotly/plotly/io/_base_renderers.py b/packages/python/plotly/plotly/io/_base_renderers.py
index 2142d1a7562..f4ccd0c0f88 100644
--- a/packages/python/plotly/plotly/io/_base_renderers.py
+++ b/packages/python/plotly/plotly/io/_base_renderers.py
@@ -236,7 +236,7 @@ def __init__(self, width=None, height=None, scale=None, engine="auto"):
 window.PlotlyConfig = {MathJaxConfig: 'local'};"""
 
 _mathjax_config = """\
-if (window.MathJax) {MathJax.Hub.Config({SVG: {font: "STIX-Web"}});}"""
+if (window.MathJax && window.MathJax.Hub && window.MathJax.Hub.Config) {window.MathJax.Hub.Config({SVG: {font: "STIX-Web"}});}"""
 
 
 class HtmlRenderer(MimetypeRenderer):
diff --git a/packages/python/plotly/plotly/io/_html.py b/packages/python/plotly/plotly/io/_html.py
index d4f5d094065..b6f61facc5a 100644
--- a/packages/python/plotly/plotly/io/_html.py
+++ b/packages/python/plotly/plotly/io/_html.py
@@ -20,7 +20,7 @@
 
 _mathjax_config = """\
 <script type="text/javascript">\
-if (window.MathJax) {MathJax.Hub.Config({SVG: {font: "STIX-Web"}});}\
+if (window.MathJax && window.MathJax.Hub && && window.MathJax.Hub.Config) {window.MathJax.Hub.Config({SVG: {font: "STIX-Web"}});}\
 </script>"""
 
 
diff --git a/packages/python/plotly/plotly/offline/offline.py b/packages/python/plotly/plotly/offline/offline.py
index 7afc79d85f0..3060b67d12f 100644
--- a/packages/python/plotly/plotly/offline/offline.py
+++ b/packages/python/plotly/plotly/offline/offline.py
@@ -190,7 +190,7 @@ def _get_jconfig(config=None):
 
 _mathjax_config = """\
 <script type="text/javascript">\
-if (window.MathJax) {MathJax.Hub.Config({SVG: {font: "STIX-Web"}});}\
+if (window.MathJax && window.MathJax.Hub && window.MathJax.Hub.Config) {window.MathJax.Hub.Config({SVG: {font: "STIX-Web"}});}\
 </script>"""