Most pandas operations return copies of the Series/DataFrame. To make the changes "stick",
you'll need to either assign to a new variable:
sorted_df = df.sort_values("col1")
or overwrite the original one:
df = df.sort_values("col1")
Note
You will see an inplace=True or copy=False keyword argument available for
some methods:
df.replace(5, inplace=True)There is an active discussion about deprecating and removing inplace and copy for
most methods (e.g. dropna) except for a very small subset of methods
(including replace). Both keywords won't be
necessary anymore in the context of Copy-on-Write. The proposal can be found
[here](pandas-dev#51466).