diff --git a/pandas/core/series.py b/pandas/core/series.py
index 3d1bd8ebb03cb..b700677747e44 100644
--- a/pandas/core/series.py
+++ b/pandas/core/series.py
@@ -3141,6 +3141,10 @@ def combine_first(self, other) -> Series:
         """
         from pandas.core.reshape.concat import concat
 
+        # Change None values to NaN
+        self.fillna(value=np.nan, inplace=True)
+        other.fillna(value=np.nan, inplace=True)
+
         if self.dtype == other.dtype:
             if self.index.equals(other.index):
                 return self.mask(self.isna(), other)