diff --git a/pandas/core/computation/eval.py b/pandas/core/computation/eval.py
index ce0c50a810ab1..0c99e5e7bdc54 100644
--- a/pandas/core/computation/eval.py
+++ b/pandas/core/computation/eval.py
@@ -389,6 +389,9 @@ def eval(
             # to use a non-numeric indexer
             try:
                 with warnings.catch_warnings(record=True):
+                    warnings.filterwarnings(
+                        "always", "Setting a value on a view", FutureWarning
+                    )
                     # TODO: Filter the warnings we actually care about here.
                     if inplace and isinstance(target, NDFrame):
                         target.loc[:, assigner] = ret
diff --git a/pandas/core/frame.py b/pandas/core/frame.py
index c3696be0579b0..956e84867709f 100644
--- a/pandas/core/frame.py
+++ b/pandas/core/frame.py
@@ -4857,6 +4857,7 @@ def eval(self, expr: str, *, inplace: bool = False, **kwargs) -> Any | None:
 
         inplace = validate_bool_kwarg(inplace, "inplace")
         kwargs["level"] = kwargs.pop("level", 0) + 1
+        # TODO(CoW) those index/column resolvers create unnecessary refs to `self`
         index_resolvers = self._get_index_resolvers()
         column_resolvers = self._get_cleaned_column_resolvers()
         resolvers = column_resolvers, index_resolvers
diff --git a/pandas/core/internals/blocks.py b/pandas/core/internals/blocks.py
index a3c2ede55dabf..ab9209d509995 100644
--- a/pandas/core/internals/blocks.py
+++ b/pandas/core/internals/blocks.py
@@ -1737,13 +1737,14 @@ def round(self, decimals: int, using_cow: bool = False) -> Self:
         # has no attribute "round"
         values = self.values.round(decimals)  # type: ignore[union-attr]
         if values is self.values:
-            refs = self.refs
             if not using_cow:
                 # Normally would need to do this before, but
                 # numpy only returns same array when round operation
                 # is no-op
                 # https://github.com/numpy/numpy/blob/486878b37fc7439a3b2b87747f50db9b62fea8eb/numpy/core/src/multiarray/calculation.c#L625-L636
                 values = values.copy()
+            else:
+                refs = self.refs
         return self.make_block_same_class(values, refs=refs)
 
     # ---------------------------------------------------------------------
diff --git a/pandas/core/internals/managers.py b/pandas/core/internals/managers.py
index 13c039cef3f91..2e20e97ca53b2 100644
--- a/pandas/core/internals/managers.py
+++ b/pandas/core/internals/managers.py
@@ -1332,7 +1332,13 @@ def column_setitem(
         This is a method on the BlockManager level, to avoid creating an
         intermediate Series at the DataFrame level (`s = df[loc]; s[idx] = value`)
         """
-        if using_copy_on_write() and not self._has_no_reference(loc):
+        if warn_copy_on_write() and not self._has_no_reference(loc):
+            warnings.warn(
+                COW_WARNING_GENERAL_MSG,
+                FutureWarning,
+                stacklevel=find_stack_level(),
+            )
+        elif using_copy_on_write() and not self._has_no_reference(loc):
             blkno = self.blknos[loc]
             # Split blocks to only copy the column we want to modify
             blk_loc = self.blklocs[loc]
diff --git a/pandas/tests/computation/test_eval.py b/pandas/tests/computation/test_eval.py
index 2311ce928ee27..40c3069dfeebf 100644
--- a/pandas/tests/computation/test_eval.py
+++ b/pandas/tests/computation/test_eval.py
@@ -1164,7 +1164,9 @@ def test_assignment_single_assign_new(self):
         df.eval("c = a + b", inplace=True)
         tm.assert_frame_equal(df, expected)
 
-    def test_assignment_single_assign_local_overlap(self):
+    # TODO(CoW-warn) this should not warn (DataFrame.eval creates refs to self)
+    @pytest.mark.filterwarnings("ignore:Setting a value on a view:FutureWarning")
+    def test_assignment_single_assign_local_overlap(self, warn_copy_on_write):
         df = DataFrame(
             np.random.default_rng(2).standard_normal((5, 2)), columns=list("ab")
         )
@@ -1218,6 +1220,8 @@ def test_column_in(self):
         tm.assert_series_equal(result, expected, check_names=False)
 
     @pytest.mark.xfail(reason="Unknown: Omitted test_ in name prior.")
+    # TODO(CoW-warn) this should not warn (DataFrame.eval creates refs to self)
+    @pytest.mark.filterwarnings("ignore:Setting a value on a view:FutureWarning")
     def test_assignment_not_inplace(self):
         # see gh-9297
         df = DataFrame(
@@ -1897,13 +1901,14 @@ def test_eval_no_support_column_name(request, column):
     tm.assert_frame_equal(result, expected)
 
 
-def test_set_inplace(using_copy_on_write):
+def test_set_inplace(using_copy_on_write, warn_copy_on_write):
     # https://github.com/pandas-dev/pandas/issues/47449
     # Ensure we don't only update the DataFrame inplace, but also the actual
     # column values, such that references to this column also get updated
     df = DataFrame({"A": [1, 2, 3], "B": [4, 5, 6], "C": [7, 8, 9]})
     result_view = df[:]
     ser = df["A"]
+    # with tm.assert_cow_warning(warn_copy_on_write):
     df.eval("A = B + C", inplace=True)
     expected = DataFrame({"A": [11, 13, 15], "B": [4, 5, 6], "C": [7, 8, 9]})
     tm.assert_frame_equal(df, expected)
diff --git a/pandas/tests/copy_view/test_constructors.py b/pandas/tests/copy_view/test_constructors.py
index 221bf8759875f..89384a4ef6ba6 100644
--- a/pandas/tests/copy_view/test_constructors.py
+++ b/pandas/tests/copy_view/test_constructors.py
@@ -242,8 +242,8 @@ def test_dataframe_from_dict_of_series(
     assert np.shares_memory(get_array(result, "a"), get_array(s1))
 
     # mutating the new dataframe doesn't mutate original
-    # TODO(CoW-warn) this should also warn
-    result.iloc[0, 0] = 10
+    with tm.assert_cow_warning(warn_copy_on_write):
+        result.iloc[0, 0] = 10
     if using_copy_on_write:
         assert not np.shares_memory(get_array(result, "a"), get_array(s1))
         tm.assert_series_equal(s1, s1_orig)
diff --git a/pandas/tests/copy_view/test_core_functionalities.py b/pandas/tests/copy_view/test_core_functionalities.py
index bfdf2b92fd326..97d77ef33d849 100644
--- a/pandas/tests/copy_view/test_core_functionalities.py
+++ b/pandas/tests/copy_view/test_core_functionalities.py
@@ -28,27 +28,32 @@ def test_setitem_dont_track_unnecessary_references(using_copy_on_write):
     assert np.shares_memory(arr, get_array(df, "a"))
 
 
-def test_setitem_with_view_copies(using_copy_on_write):
+def test_setitem_with_view_copies(using_copy_on_write, warn_copy_on_write):
     df = DataFrame({"a": [1, 2, 3], "b": 1, "c": 1})
     view = df[:]
     expected = df.copy()
 
     df["b"] = 100
     arr = get_array(df, "a")
-    df.iloc[0, 0] = 100  # Check that we correctly track reference
+    with tm.assert_cow_warning(warn_copy_on_write):
+        df.iloc[0, 0] = 100  # Check that we correctly track reference
     if using_copy_on_write:
         assert not np.shares_memory(arr, get_array(df, "a"))
         tm.assert_frame_equal(view, expected)
 
 
-def test_setitem_with_view_invalidated_does_not_copy(using_copy_on_write, request):
+def test_setitem_with_view_invalidated_does_not_copy(
+    using_copy_on_write, warn_copy_on_write, request
+):
     df = DataFrame({"a": [1, 2, 3], "b": 1, "c": 1})
     view = df[:]
 
     df["b"] = 100
     arr = get_array(df, "a")
     view = None  # noqa: F841
-    df.iloc[0, 0] = 100
+    # TODO(CoW-warn) false positive?
+    with tm.assert_cow_warning(warn_copy_on_write):
+        df.iloc[0, 0] = 100
     if using_copy_on_write:
         # Setitem split the block. Since the old block shared data with view
         # all the new blocks are referencing view and each other. When view
diff --git a/pandas/tests/copy_view/test_indexing.py b/pandas/tests/copy_view/test_indexing.py
index c4d5e9dbce72a..5a0ebff64a803 100644
--- a/pandas/tests/copy_view/test_indexing.py
+++ b/pandas/tests/copy_view/test_indexing.py
@@ -101,7 +101,7 @@ def test_subset_column_selection_modify_parent(backend, using_copy_on_write):
     tm.assert_frame_equal(subset, expected)
 
 
-def test_subset_row_slice(backend, using_copy_on_write):
+def test_subset_row_slice(backend, using_copy_on_write, warn_copy_on_write):
     # Case: taking a subset of the rows of a DataFrame using a slice
     # + afterwards modifying the subset
     _, DataFrame, _ = backend
@@ -121,7 +121,8 @@ def test_subset_row_slice(backend, using_copy_on_write):
         # INFO this no longer raise warning since pandas 1.4
         # with pd.option_context("chained_assignment", "warn"):
         #     with tm.assert_produces_warning(SettingWithCopyWarning):
-        subset.iloc[0, 0] = 0
+        with tm.assert_cow_warning(warn_copy_on_write):
+            subset.iloc[0, 0] = 0
 
     subset._mgr._verify_integrity()
 
@@ -334,8 +335,11 @@ def test_subset_set_with_row_indexer(
         pytest.skip("setitem with labels selects on columns")
 
     # TODO(CoW-warn) should warn
-    if using_copy_on_write or warn_copy_on_write:
+    if using_copy_on_write:
         indexer_si(subset)[indexer] = 0
+    elif warn_copy_on_write:
+        with tm.assert_cow_warning():
+            indexer_si(subset)[indexer] = 0
     else:
         # INFO iloc no longer raises warning since pandas 1.4
         warn = SettingWithCopyWarning if indexer_si is tm.setitem else None
@@ -419,7 +423,7 @@ def test_subset_set_column(backend, using_copy_on_write, warn_copy_on_write):
     "dtype", ["int64", "float64"], ids=["single-block", "mixed-block"]
 )
 def test_subset_set_column_with_loc(
-    backend, using_copy_on_write, using_array_manager, dtype
+    backend, using_copy_on_write, warn_copy_on_write, using_array_manager, dtype
 ):
     # Case: setting a single column with loc on a viewing subset
     # -> subset.loc[:, col] = value
@@ -432,6 +436,9 @@ def test_subset_set_column_with_loc(
 
     if using_copy_on_write:
         subset.loc[:, "a"] = np.array([10, 11], dtype="int64")
+    elif warn_copy_on_write:
+        with tm.assert_cow_warning():
+            subset.loc[:, "a"] = np.array([10, 11], dtype="int64")
     else:
         with pd.option_context("chained_assignment", "warn"):
             with tm.assert_produces_warning(
@@ -455,7 +462,9 @@ def test_subset_set_column_with_loc(
         tm.assert_frame_equal(df, df_orig)
 
 
-def test_subset_set_column_with_loc2(backend, using_copy_on_write, using_array_manager):
+def test_subset_set_column_with_loc2(
+    backend, using_copy_on_write, warn_copy_on_write, using_array_manager
+):
     # Case: setting a single column with loc on a viewing subset
     # -> subset.loc[:, col] = value
     # separate test for case of DataFrame of a single column -> takes a separate
@@ -467,6 +476,9 @@ def test_subset_set_column_with_loc2(backend, using_copy_on_write, using_array_m
 
     if using_copy_on_write:
         subset.loc[:, "a"] = 0
+    elif warn_copy_on_write:
+        with tm.assert_cow_warning():
+            subset.loc[:, "a"] = 0
     else:
         with pd.option_context("chained_assignment", "warn"):
             with tm.assert_produces_warning(
@@ -528,7 +540,9 @@ def test_subset_set_columns(backend, using_copy_on_write, warn_copy_on_write, dt
     [slice("a", "b"), np.array([True, True, False]), ["a", "b"]],
     ids=["slice", "mask", "array"],
 )
-def test_subset_set_with_column_indexer(backend, indexer, using_copy_on_write):
+def test_subset_set_with_column_indexer(
+    backend, indexer, using_copy_on_write, warn_copy_on_write
+):
     # Case: setting multiple columns with a column indexer on a viewing subset
     # -> subset.loc[:, [col1, col2]] = value
     _, DataFrame, _ = backend
@@ -538,6 +552,9 @@ def test_subset_set_with_column_indexer(backend, indexer, using_copy_on_write):
 
     if using_copy_on_write:
         subset.loc[:, indexer] = 0
+    elif warn_copy_on_write:
+        with tm.assert_cow_warning():
+            subset.loc[:, indexer] = 0
     else:
         with pd.option_context("chained_assignment", "warn"):
             # As of 2.0, this setitem attempts (successfully) to set values
@@ -659,10 +676,7 @@ def test_subset_chained_getitem_column(
     # modify parent -> don't modify subset
     subset = df[:]["a"][0:2]
     df._clear_item_cache()
-    # TODO(CoW-warn) should also warn for mixed block and nullable dtypes
-    with tm.assert_cow_warning(
-        warn_copy_on_write and dtype == "int64" and dtype_backend == "numpy"
-    ):
+    with tm.assert_cow_warning(warn_copy_on_write):
         df.iloc[0, 0] = 0
     expected = Series([1, 2], name="a")
     if using_copy_on_write:
@@ -765,8 +779,7 @@ def test_null_slice(backend, method, using_copy_on_write, warn_copy_on_write):
     assert df2 is not df
 
     # and those trigger CoW when mutated
-    # TODO(CoW-warn) should also warn for nullable dtypes
-    with tm.assert_cow_warning(warn_copy_on_write and dtype_backend == "numpy"):
+    with tm.assert_cow_warning(warn_copy_on_write):
         df2.iloc[0, 0] = 0
     if using_copy_on_write:
         tm.assert_frame_equal(df, df_orig)
@@ -884,10 +897,10 @@ def test_series_subset_set_with_indexer(
 # del operator
 
 
-def test_del_frame(backend, using_copy_on_write):
+def test_del_frame(backend, using_copy_on_write, warn_copy_on_write):
     # Case: deleting a column with `del` on a viewing child dataframe should
     # not modify parent + update the references
-    _, DataFrame, _ = backend
+    dtype_backend, DataFrame, _ = backend
     df = DataFrame({"a": [1, 2, 3], "b": [4, 5, 6], "c": [0.1, 0.2, 0.3]})
     df_orig = df.copy()
     df2 = df[:]
@@ -901,11 +914,14 @@ def test_del_frame(backend, using_copy_on_write):
     tm.assert_frame_equal(df2, df_orig[["a", "c"]])
     df2._mgr._verify_integrity()
 
-    df.loc[0, "b"] = 200
+    # TODO(CoW-warn) false positive, this should not warn?
+    with tm.assert_cow_warning(warn_copy_on_write and dtype_backend == "numpy"):
+        df.loc[0, "b"] = 200
     assert np.shares_memory(get_array(df, "a"), get_array(df2, "a"))
     df_orig = df.copy()
 
-    df2.loc[0, "a"] = 100
+    with tm.assert_cow_warning(warn_copy_on_write):
+        df2.loc[0, "a"] = 100
     if using_copy_on_write:
         # modifying child after deleting a column still doesn't update parent
         tm.assert_frame_equal(df, df_orig)
@@ -1109,7 +1125,6 @@ def test_set_value_copy_only_necessary_column(
 ):
     # When setting inplace, only copy column that is modified instead of the whole
     # block (by splitting the block)
-    single_block = isinstance(col[0], int)
     df = DataFrame({"a": [1, 2, 3], "b": [4, 5, 6], "c": col})
     df_orig = df.copy()
     view = df[:]
@@ -1120,11 +1135,7 @@ def test_set_value_copy_only_necessary_column(
         ):
             indexer_func(df)[indexer] = val
     else:
-        # TODO(CoW-warn) should also warn in the other cases
-        with tm.assert_cow_warning(
-            warn_copy_on_write
-            and not (indexer[0] == slice(None) or (not single_block and val == 100))
-        ):
+        with tm.assert_cow_warning(warn_copy_on_write):
             indexer_func(df)[indexer] = val
 
     if using_copy_on_write:
diff --git a/pandas/tests/copy_view/test_interp_fillna.py b/pandas/tests/copy_view/test_interp_fillna.py
index 5507e81d04e2a..b2f3312abf8b5 100644
--- a/pandas/tests/copy_view/test_interp_fillna.py
+++ b/pandas/tests/copy_view/test_interp_fillna.py
@@ -324,11 +324,12 @@ def test_fillna_ea_noop_shares_memory(
 
 
 def test_fillna_inplace_ea_noop_shares_memory(
-    using_copy_on_write, any_numeric_ea_and_arrow_dtype
+    using_copy_on_write, warn_copy_on_write, any_numeric_ea_and_arrow_dtype
 ):
     df = DataFrame({"a": [1, NA, 3], "b": 1}, dtype=any_numeric_ea_and_arrow_dtype)
     df_orig = df.copy()
     view = df[:]
+    # TODO(CoW-warn)
     df.fillna(100, inplace=True)
 
     if isinstance(df["a"].dtype, ArrowDtype) or using_copy_on_write:
@@ -342,7 +343,9 @@ def test_fillna_inplace_ea_noop_shares_memory(
         assert not df._mgr._has_no_reference(1)
         assert not view._mgr._has_no_reference(1)
 
-    df.iloc[0, 1] = 100
+    # TODO(CoW-warn) should this warn for ArrowDtype?
+    with tm.assert_cow_warning(warn_copy_on_write):
+        df.iloc[0, 1] = 100
     if isinstance(df["a"].dtype, ArrowDtype) or using_copy_on_write:
         tm.assert_frame_equal(df_orig, view)
     else:
diff --git a/pandas/tests/copy_view/test_methods.py b/pandas/tests/copy_view/test_methods.py
index 73bb9b4a71741..faa1eec09d30b 100644
--- a/pandas/tests/copy_view/test_methods.py
+++ b/pandas/tests/copy_view/test_methods.py
@@ -39,7 +39,7 @@ def test_copy(using_copy_on_write):
     assert df.iloc[0, 0] == 1
 
 
-def test_copy_shallow(using_copy_on_write):
+def test_copy_shallow(using_copy_on_write, warn_copy_on_write):
     df = DataFrame({"a": [1, 2, 3], "b": [4, 5, 6], "c": [0.1, 0.2, 0.3]})
     df_copy = df.copy(deep=False)
 
@@ -69,7 +69,8 @@ def test_copy_shallow(using_copy_on_write):
         assert np.shares_memory(get_array(df_copy, "c"), get_array(df, "c"))
     else:
         # mutating shallow copy does mutate original
-        df_copy.iloc[0, 0] = 0
+        with tm.assert_cow_warning(warn_copy_on_write):
+            df_copy.iloc[0, 0] = 0
         assert df.iloc[0, 0] == 0
         # and still shares memory
         assert np.shares_memory(get_array(df_copy, "a"), get_array(df, "a"))
@@ -546,7 +547,7 @@ def test_shift_columns(using_copy_on_write, warn_copy_on_write):
         tm.assert_frame_equal(df2, expected)
 
 
-def test_pop(using_copy_on_write):
+def test_pop(using_copy_on_write, warn_copy_on_write):
     df = DataFrame({"a": [1, 2, 3], "b": [4, 5, 6], "c": [0.1, 0.2, 0.3]})
     df_orig = df.copy()
     view_original = df[:]
@@ -558,7 +559,8 @@ def test_pop(using_copy_on_write):
     if using_copy_on_write:
         result.iloc[0] = 0
         assert not np.shares_memory(result.values, get_array(view_original, "a"))
-    df.iloc[0, 0] = 0
+    with tm.assert_cow_warning(warn_copy_on_write):
+        df.iloc[0, 0] = 0
     if using_copy_on_write:
         assert not np.shares_memory(get_array(df, "b"), get_array(view_original, "b"))
         tm.assert_frame_equal(view_original, df_orig)
@@ -744,7 +746,7 @@ def test_swapaxes_read_only_array():
     ],
     ids=["shallow-copy", "reset_index", "rename", "select_dtypes"],
 )
-def test_chained_methods(request, method, idx, using_copy_on_write):
+def test_chained_methods(request, method, idx, using_copy_on_write, warn_copy_on_write):
     df = DataFrame({"a": [1, 2, 3], "b": [4, 5, 6], "c": [0.1, 0.2, 0.3]})
     df_orig = df.copy()
 
@@ -753,13 +755,15 @@ def test_chained_methods(request, method, idx, using_copy_on_write):
 
     # modify df2 -> don't modify df
     df2 = method(df)
-    df2.iloc[0, idx] = 0
+    with tm.assert_cow_warning(warn_copy_on_write and df2_is_view):
+        df2.iloc[0, idx] = 0
     if not df2_is_view:
         tm.assert_frame_equal(df, df_orig)
 
     # modify df -> don't modify df2
     df2 = method(df)
-    df.iloc[0, 0] = 0
+    with tm.assert_cow_warning(warn_copy_on_write and df2_is_view):
+        df.iloc[0, 0] = 0
     if not df2_is_view:
         tm.assert_frame_equal(df2.iloc[:, idx:], df_orig)
 
@@ -908,7 +912,7 @@ def test_dropna_series(using_copy_on_write, val):
         lambda df: df.tail(3),
     ],
 )
-def test_head_tail(method, using_copy_on_write):
+def test_head_tail(method, using_copy_on_write, warn_copy_on_write):
     df = DataFrame({"a": [1, 2, 3], "b": [0.1, 0.2, 0.3]})
     df_orig = df.copy()
     df2 = method(df)
@@ -921,14 +925,16 @@ def test_head_tail(method, using_copy_on_write):
         assert not np.shares_memory(get_array(df2, "b"), get_array(df, "b"))
 
     # modify df2 to trigger CoW for that block
-    df2.iloc[0, 0] = 0
+    with tm.assert_cow_warning(warn_copy_on_write):
+        df2.iloc[0, 0] = 0
     if using_copy_on_write:
         assert not np.shares_memory(get_array(df2, "b"), get_array(df, "b"))
         assert not np.shares_memory(get_array(df2, "a"), get_array(df, "a"))
     else:
         # without CoW enabled, head and tail return views. Mutating df2 also mutates df.
         assert np.shares_memory(get_array(df2, "b"), get_array(df, "b"))
-        df2.iloc[0, 0] = 1
+        with tm.assert_cow_warning(warn_copy_on_write):
+            df2.iloc[0, 0] = 1
     tm.assert_frame_equal(df, df_orig)
 
 
@@ -1160,7 +1166,7 @@ def test_sort_values_inplace(using_copy_on_write, obj, kwargs, warn_copy_on_writ
 
 
 @pytest.mark.parametrize("decimals", [-1, 0, 1])
-def test_round(using_copy_on_write, decimals):
+def test_round(using_copy_on_write, warn_copy_on_write, decimals):
     df = DataFrame({"a": [1, 2], "b": "c"})
     df_orig = df.copy()
     df2 = df.round(decimals=decimals)
@@ -1175,6 +1181,7 @@ def test_round(using_copy_on_write, decimals):
             assert not np.shares_memory(get_array(df2, "a"), get_array(df, "a"))
     else:
         assert not np.shares_memory(get_array(df2, "b"), get_array(df, "b"))
+        assert not np.shares_memory(get_array(df2, "a"), get_array(df, "a"))
 
     df2.iloc[0, 1] = "d"
     df2.iloc[0, 0] = 4
@@ -1756,13 +1763,15 @@ def test_xs_multiindex(
     tm.assert_frame_equal(df, df_orig)
 
 
-def test_update_frame(using_copy_on_write):
+def test_update_frame(using_copy_on_write, warn_copy_on_write):
     df1 = DataFrame({"a": [1.0, 2.0, 3.0], "b": [4.0, 5.0, 6.0]})
     df2 = DataFrame({"b": [100.0]}, index=[1])
     df1_orig = df1.copy()
     view = df1[:]
 
-    df1.update(df2)
+    # TODO(CoW) better warning message?
+    with tm.assert_cow_warning(warn_copy_on_write):
+        df1.update(df2)
 
     expected = DataFrame({"a": [1.0, 2.0, 3.0], "b": [4.0, 100.0, 6.0]})
     tm.assert_frame_equal(df1, expected)
@@ -1947,7 +1956,7 @@ def test_eval(using_copy_on_write):
     tm.assert_frame_equal(df, df_orig)
 
 
-def test_eval_inplace(using_copy_on_write):
+def test_eval_inplace(using_copy_on_write, warn_copy_on_write):
     df = DataFrame({"a": [1, 2, 3], "b": 1})
     df_orig = df.copy()
     df_view = df[:]
@@ -1955,6 +1964,7 @@ def test_eval_inplace(using_copy_on_write):
     df.eval("c = a+b", inplace=True)
     assert np.shares_memory(get_array(df, "a"), get_array(df_view, "a"))
 
-    df.iloc[0, 0] = 100
+    with tm.assert_cow_warning(warn_copy_on_write):
+        df.iloc[0, 0] = 100
     if using_copy_on_write:
         tm.assert_frame_equal(df_view, df_orig)
diff --git a/pandas/tests/extension/base/setitem.py b/pandas/tests/extension/base/setitem.py
index 83e2c795b8b5e..b8ede450b3c1a 100644
--- a/pandas/tests/extension/base/setitem.py
+++ b/pandas/tests/extension/base/setitem.py
@@ -402,7 +402,7 @@ def test_setitem_frame_2d_values(self, data):
 
         orig = df.copy()
 
-        df.iloc[:] = df
+        df.iloc[:] = df.copy()
         tm.assert_frame_equal(df, orig)
 
         df.iloc[:-1] = df.iloc[:-1].copy()
diff --git a/pandas/tests/frame/indexing/test_indexing.py b/pandas/tests/frame/indexing/test_indexing.py
index 93f391b16817c..d76bfd2d7ae7c 100644
--- a/pandas/tests/frame/indexing/test_indexing.py
+++ b/pandas/tests/frame/indexing/test_indexing.py
@@ -561,7 +561,7 @@ def test_getitem_setitem_integer_slice_keyerrors(self):
 
     @td.skip_array_manager_invalid_test  # already covered in test_iloc_col_slice_view
     def test_fancy_getitem_slice_mixed(
-        self, float_frame, float_string_frame, using_copy_on_write
+        self, float_frame, float_string_frame, using_copy_on_write, warn_copy_on_write
     ):
         sliced = float_string_frame.iloc[:, -3:]
         assert sliced["D"].dtype == np.float64
@@ -573,7 +573,8 @@ def test_fancy_getitem_slice_mixed(
 
         assert np.shares_memory(sliced["C"]._values, float_frame["C"]._values)
 
-        sliced.loc[:, "C"] = 4.0
+        with tm.assert_cow_warning(warn_copy_on_write):
+            sliced.loc[:, "C"] = 4.0
         if not using_copy_on_write:
             assert (float_frame["C"] == 4).all()
 
@@ -1049,7 +1050,7 @@ def test_iloc_row(self):
         expected = df.reindex(df.index[[1, 2, 4, 6]])
         tm.assert_frame_equal(result, expected)
 
-    def test_iloc_row_slice_view(self, using_copy_on_write, request):
+    def test_iloc_row_slice_view(self, using_copy_on_write, warn_copy_on_write):
         df = DataFrame(
             np.random.default_rng(2).standard_normal((10, 4)), index=range(0, 20, 2)
         )
@@ -1062,9 +1063,9 @@ def test_iloc_row_slice_view(self, using_copy_on_write, request):
         assert np.shares_memory(df[2], subset[2])
 
         exp_col = original[2].copy()
-        subset.loc[:, 2] = 0.0
-        if not using_copy_on_write:
+        with tm.assert_cow_warning(warn_copy_on_write):
             subset.loc[:, 2] = 0.0
+        if not using_copy_on_write:
             exp_col._values[4:8] = 0.0
 
             # With the enforcement of GH#45333 in 2.0, this remains a view
@@ -1094,7 +1095,9 @@ def test_iloc_col(self):
         expected = df.reindex(columns=df.columns[[1, 2, 4, 6]])
         tm.assert_frame_equal(result, expected)
 
-    def test_iloc_col_slice_view(self, using_array_manager, using_copy_on_write):
+    def test_iloc_col_slice_view(
+        self, using_array_manager, using_copy_on_write, warn_copy_on_write
+    ):
         df = DataFrame(
             np.random.default_rng(2).standard_normal((4, 10)), columns=range(0, 20, 2)
         )
@@ -1105,7 +1108,8 @@ def test_iloc_col_slice_view(self, using_array_manager, using_copy_on_write):
             # verify slice is view
             assert np.shares_memory(df[8]._values, subset[8]._values)
 
-            subset.loc[:, 8] = 0.0
+            with tm.assert_cow_warning(warn_copy_on_write):
+                subset.loc[:, 8] = 0.0
 
             assert (df[8] == 0).all()
 
@@ -1388,12 +1392,13 @@ def test_loc_setitem_rhs_frame(self, idxr, val, warn):
         tm.assert_frame_equal(df, expected)
 
     @td.skip_array_manager_invalid_test
-    def test_iloc_setitem_enlarge_no_warning(self):
+    def test_iloc_setitem_enlarge_no_warning(self, warn_copy_on_write):
         # GH#47381
         df = DataFrame(columns=["a", "b"])
         expected = df.copy()
         view = df[:]
-        with tm.assert_produces_warning(None):
+        # TODO(CoW-warn) false positive: shouldn't warn in case of enlargement?
+        with tm.assert_produces_warning(FutureWarning if warn_copy_on_write else None):
             df.iloc[:, 0] = np.array([1, 2], dtype=np.float64)
         tm.assert_frame_equal(view, expected)
 
diff --git a/pandas/tests/frame/indexing/test_setitem.py b/pandas/tests/frame/indexing/test_setitem.py
index 49dd7a3c4df9b..4e37d8ff3c024 100644
--- a/pandas/tests/frame/indexing/test_setitem.py
+++ b/pandas/tests/frame/indexing/test_setitem.py
@@ -816,7 +816,7 @@ def test_setitem_object_array_of_tzaware_datetimes(self, idx, expected):
 
 
 class TestDataFrameSetItemWithExpansion:
-    def test_setitem_listlike_views(self, using_copy_on_write):
+    def test_setitem_listlike_views(self, using_copy_on_write, warn_copy_on_write):
         # GH#38148
         df = DataFrame({"a": [1, 2, 3], "b": [4, 4, 6]})
 
@@ -827,7 +827,8 @@ def test_setitem_listlike_views(self, using_copy_on_write):
         df[["c", "d"]] = np.array([[0.1, 0.2], [0.3, 0.4], [0.4, 0.5]])
 
         # edit in place the first column to check view semantics
-        df.iloc[0, 0] = 100
+        with tm.assert_cow_warning(warn_copy_on_write):
+            df.iloc[0, 0] = 100
 
         if using_copy_on_write:
             expected = Series([1, 2, 3], name="a")
diff --git a/pandas/tests/frame/methods/test_diff.py b/pandas/tests/frame/methods/test_diff.py
index 1b7e669232592..bef18dbaf8a8a 100644
--- a/pandas/tests/frame/methods/test_diff.py
+++ b/pandas/tests/frame/methods/test_diff.py
@@ -89,7 +89,7 @@ def test_diff_datetime_with_nat_zero_periods(self, tz):
         # diff on NaT values should give NaT, not timedelta64(0)
         dti = date_range("2016-01-01", periods=4, tz=tz)
         ser = Series(dti)
-        df = ser.to_frame()
+        df = ser.to_frame().copy()
 
         df[1] = ser.copy()
 
diff --git a/pandas/tests/frame/methods/test_fillna.py b/pandas/tests/frame/methods/test_fillna.py
index 52b4b64ee279f..a32f290d3aa12 100644
--- a/pandas/tests/frame/methods/test_fillna.py
+++ b/pandas/tests/frame/methods/test_fillna.py
@@ -20,14 +20,18 @@
 
 
 class TestFillNA:
-    def test_fillna_dict_inplace_nonunique_columns(self, using_copy_on_write):
+    def test_fillna_dict_inplace_nonunique_columns(
+        self, using_copy_on_write, warn_copy_on_write
+    ):
         df = DataFrame(
             {"A": [np.nan] * 3, "B": [NaT, Timestamp(1), NaT], "C": [np.nan, "foo", 2]}
         )
         df.columns = ["A", "A", "A"]
         orig = df[:]
 
-        df.fillna({"A": 2}, inplace=True)
+        # TODO(CoW-warn) better warning message
+        with tm.assert_cow_warning(warn_copy_on_write):
+            df.fillna({"A": 2}, inplace=True)
         # The first and third columns can be set inplace, while the second cannot.
 
         expected = DataFrame(
@@ -733,12 +737,16 @@ def test_fillna_inplace_with_columns_limit_and_value(self):
 
     @td.skip_array_manager_invalid_test
     @pytest.mark.parametrize("val", [-1, {"x": -1, "y": -1}])
-    def test_inplace_dict_update_view(self, val, using_copy_on_write):
+    def test_inplace_dict_update_view(
+        self, val, using_copy_on_write, warn_copy_on_write
+    ):
         # GH#47188
         df = DataFrame({"x": [np.nan, 2], "y": [np.nan, 2]})
         df_orig = df.copy()
         result_view = df[:]
-        df.fillna(val, inplace=True)
+        # TODO(CoW-warn) better warning message + should warn in all cases
+        with tm.assert_cow_warning(warn_copy_on_write and not isinstance(val, int)):
+            df.fillna(val, inplace=True)
         expected = DataFrame({"x": [-1, 2.0], "y": [-1.0, 2]})
         tm.assert_frame_equal(df, expected)
         if using_copy_on_write:
diff --git a/pandas/tests/frame/methods/test_rename.py b/pandas/tests/frame/methods/test_rename.py
index b965a5d973fb6..c3bc96b44c807 100644
--- a/pandas/tests/frame/methods/test_rename.py
+++ b/pandas/tests/frame/methods/test_rename.py
@@ -164,12 +164,13 @@ def test_rename_multiindex(self):
         renamed = df.rename(index={"foo1": "foo3", "bar2": "bar3"}, level=0)
         tm.assert_index_equal(renamed.index, new_index)
 
-    def test_rename_nocopy(self, float_frame, using_copy_on_write):
+    def test_rename_nocopy(self, float_frame, using_copy_on_write, warn_copy_on_write):
         renamed = float_frame.rename(columns={"C": "foo"}, copy=False)
 
         assert np.shares_memory(renamed["foo"]._values, float_frame["C"]._values)
 
-        renamed.loc[:, "foo"] = 1.0
+        with tm.assert_cow_warning(warn_copy_on_write):
+            renamed.loc[:, "foo"] = 1.0
         if using_copy_on_write:
             assert not (float_frame["C"] == 1.0).all()
         else:
diff --git a/pandas/tests/frame/methods/test_to_dict_of_blocks.py b/pandas/tests/frame/methods/test_to_dict_of_blocks.py
index 471b9eaf936ad..28973fe0d7900 100644
--- a/pandas/tests/frame/methods/test_to_dict_of_blocks.py
+++ b/pandas/tests/frame/methods/test_to_dict_of_blocks.py
@@ -30,6 +30,7 @@ def test_copy_blocks(self, float_frame):
         # make sure we did not change the original DataFrame
         assert _last_df is not None and not _last_df[column].equals(df[column])
 
+    @pytest.mark.filterwarnings("ignore:Setting a value on a view:FutureWarning")
     def test_no_copy_blocks(self, float_frame, using_copy_on_write):
         # GH#9607
         df = DataFrame(float_frame, copy=True)
diff --git a/pandas/tests/frame/methods/test_update.py b/pandas/tests/frame/methods/test_update.py
index 5738a25f26fcb..0d32788b04b03 100644
--- a/pandas/tests/frame/methods/test_update.py
+++ b/pandas/tests/frame/methods/test_update.py
@@ -154,13 +154,15 @@ def test_update_with_different_dtype(self, using_copy_on_write):
         tm.assert_frame_equal(df, expected)
 
     @td.skip_array_manager_invalid_test
-    def test_update_modify_view(self, using_copy_on_write):
+    def test_update_modify_view(self, using_copy_on_write, warn_copy_on_write):
         # GH#47188
         df = DataFrame({"A": ["1", np.nan], "B": ["100", np.nan]})
         df2 = DataFrame({"A": ["a", "x"], "B": ["100", "200"]})
         df2_orig = df2.copy()
         result_view = df2[:]
-        df2.update(df)
+        # TODO(CoW-warn) better warning message
+        with tm.assert_cow_warning(warn_copy_on_write):
+            df2.update(df)
         expected = DataFrame({"A": ["1", "x"], "B": ["100", "200"]})
         tm.assert_frame_equal(df2, expected)
         if using_copy_on_write:
diff --git a/pandas/tests/groupby/methods/test_nth.py b/pandas/tests/groupby/methods/test_nth.py
index e3005c9b971ec..4a5571d0daa42 100644
--- a/pandas/tests/groupby/methods/test_nth.py
+++ b/pandas/tests/groupby/methods/test_nth.py
@@ -44,7 +44,9 @@ def test_first_last_nth(df):
     grouped["B"].last()
     grouped["B"].nth(0)
 
+    df = df.copy()
     df.loc[df["A"] == "foo", "B"] = np.nan
+    grouped = df.groupby("A")
     assert isna(grouped["B"].first()["foo"])
     assert isna(grouped["B"].last()["foo"])
     assert isna(grouped["B"].nth(0).iloc[0])
diff --git a/pandas/tests/groupby/methods/test_quantile.py b/pandas/tests/groupby/methods/test_quantile.py
index d949e5e36fa81..361a8c27fbf9d 100644
--- a/pandas/tests/groupby/methods/test_quantile.py
+++ b/pandas/tests/groupby/methods/test_quantile.py
@@ -447,8 +447,7 @@ def test_timestamp_groupby_quantile(unit):
 def test_groupby_quantile_dt64tz_period():
     # GH#51373
     dti = pd.date_range("2016-01-01", periods=1000)
-    ser = pd.Series(dti)
-    df = ser.to_frame()
+    df = pd.Series(dti).to_frame().copy()
     df[1] = dti.tz_localize("US/Pacific")
     df[2] = dti.to_period("D")
     df[3] = dti - dti[0]
diff --git a/pandas/tests/indexing/multiindex/test_setitem.py b/pandas/tests/indexing/multiindex/test_setitem.py
index 3237c8f52797a..e31b675efb69a 100644
--- a/pandas/tests/indexing/multiindex/test_setitem.py
+++ b/pandas/tests/indexing/multiindex/test_setitem.py
@@ -201,7 +201,9 @@ def test_multiindex_assignment(self):
         df.loc[4, "d"] = arr
         tm.assert_series_equal(df.loc[4, "d"], Series(arr, index=[8, 10], name="d"))
 
-    def test_multiindex_assignment_single_dtype(self, using_copy_on_write):
+    def test_multiindex_assignment_single_dtype(
+        self, using_copy_on_write, warn_copy_on_write
+    ):
         # GH3777 part 2b
         # single dtype
         arr = np.array([0.0, 1.0])
@@ -215,6 +217,8 @@ def test_multiindex_assignment_single_dtype(self, using_copy_on_write):
         view = df["c"].iloc[:2].values
 
         # arr can be losslessly cast to int, so this setitem is inplace
+        # INFO(CoW-warn) this does not warn because we directly took .values
+        # above, so no reference to a pandas object is alive for `view`
         df.loc[4, "c"] = arr
         exp = Series(arr, index=[8, 10], name="c", dtype="int64")
         result = df.loc[4, "c"]
@@ -234,7 +238,8 @@ def test_multiindex_assignment_single_dtype(self, using_copy_on_write):
         tm.assert_series_equal(result, exp)
 
         # scalar ok
-        df.loc[4, "c"] = 10
+        with tm.assert_cow_warning(warn_copy_on_write):
+            df.loc[4, "c"] = 10
         exp = Series(10, index=[8, 10], name="c", dtype="float64")
         tm.assert_series_equal(df.loc[4, "c"], exp)
 
@@ -248,7 +253,8 @@ def test_multiindex_assignment_single_dtype(self, using_copy_on_write):
 
         # But with a length-1 listlike column indexer this behaves like
         #  `df.loc[4, "c"] = 0
-        df.loc[4, ["c"]] = [0]
+        with tm.assert_cow_warning(warn_copy_on_write):
+            df.loc[4, ["c"]] = [0]
         assert (df.loc[4, "c"] == 0).all()
 
     def test_groupby_example(self):
diff --git a/pandas/tests/indexing/test_iat.py b/pandas/tests/indexing/test_iat.py
index b4c4b81ac9cfb..5b8c4f2d4b9b9 100644
--- a/pandas/tests/indexing/test_iat.py
+++ b/pandas/tests/indexing/test_iat.py
@@ -41,11 +41,10 @@ def test_iat_setitem_item_cache_cleared(
 
     # previously this iat setting would split the block and fail to clear
     #  the item_cache.
-    with tm.assert_cow_warning(warn_copy_on_write and indexer_ial is tm.iloc):
+    with tm.assert_cow_warning(warn_copy_on_write):
         indexer_ial(df)[7, 0] = 9999
 
-    # TODO(CoW-warn) should also warn for iat?
-    with tm.assert_cow_warning(warn_copy_on_write and indexer_ial is tm.iloc):
+    with tm.assert_cow_warning(warn_copy_on_write):
         indexer_ial(df)[7, 1] = 1234
 
     assert df.iat[7, 1] == 1234
diff --git a/pandas/tests/indexing/test_iloc.py b/pandas/tests/indexing/test_iloc.py
index 5c0c1b42ca963..b3f93cbfd4113 100644
--- a/pandas/tests/indexing/test_iloc.py
+++ b/pandas/tests/indexing/test_iloc.py
@@ -850,9 +850,8 @@ def test_identity_slice_returns_new_object(
 
         # Setting using .loc[:, "a"] sets inplace so alters both sliced and orig
         # depending on CoW
-        # TODO(CoW-warn) this should warn
-        # with tm.assert_cow_warning(warn_copy_on_write):
-        original_df.loc[:, "a"] = [4, 4, 4]
+        with tm.assert_cow_warning(warn_copy_on_write):
+            original_df.loc[:, "a"] = [4, 4, 4]
         if using_copy_on_write:
             assert (sliced_df["a"] == [1, 2, 3]).all()
         else:
@@ -1142,7 +1141,7 @@ def test_iloc_getitem_with_duplicates2(self):
         expected = df.take([0], axis=1)
         tm.assert_frame_equal(result, expected)
 
-    def test_iloc_interval(self):
+    def test_iloc_interval(self, warn_copy_on_write):
         # GH#17130
         df = DataFrame({Interval(1, 2): [1, 2]})
 
@@ -1155,7 +1154,9 @@ def test_iloc_interval(self):
         tm.assert_series_equal(result, expected)
 
         result = df.copy()
-        result.iloc[:, 0] += 1
+        # TODO(CoW-warn) false positive
+        with tm.assert_cow_warning(warn_copy_on_write):
+            result.iloc[:, 0] += 1
         expected = DataFrame({Interval(1, 2): [2, 3]})
         tm.assert_frame_equal(result, expected)
 
diff --git a/pandas/tests/indexing/test_loc.py b/pandas/tests/indexing/test_loc.py
index 35c50d6c705d1..96fd3f4e6fca0 100644
--- a/pandas/tests/indexing/test_loc.py
+++ b/pandas/tests/indexing/test_loc.py
@@ -828,7 +828,8 @@ def test_loc_setitem_frame_mixed_labels(self):
         df.loc[0, [1, 2]] = [5, 6]
         tm.assert_frame_equal(df, expected)
 
-    def test_loc_setitem_frame_multiples(self):
+    @pytest.mark.filterwarnings("ignore:Setting a value on a view:FutureWarning")
+    def test_loc_setitem_frame_multiples(self, warn_copy_on_write):
         # multiple setting
         df = DataFrame(
             {"A": ["foo", "bar", "baz"], "B": Series(range(3), dtype=np.int64)}
@@ -1097,9 +1098,8 @@ def test_identity_slice_returns_new_object(
 
         # Setting using .loc[:, "a"] sets inplace so alters both sliced and orig
         # depending on CoW
-        # TODO(CoW-warn) should warn
-        # with tm.assert_cow_warning(warn_copy_on_write):
-        original_df.loc[:, "a"] = [4, 4, 4]
+        with tm.assert_cow_warning(warn_copy_on_write):
+            original_df.loc[:, "a"] = [4, 4, 4]
         if using_copy_on_write:
             assert (sliced_df["a"] == [1, 2, 3]).all()
         else:
diff --git a/pandas/tests/io/test_common.py b/pandas/tests/io/test_common.py
index 018400fcfe0cf..26035d1af7f90 100644
--- a/pandas/tests/io/test_common.py
+++ b/pandas/tests/io/test_common.py
@@ -288,6 +288,8 @@ def test_read_expands_user_home_dir(
         ):
             reader(path)
 
+    # TODO(CoW-warn) avoid warnings in the stata reader code
+    @pytest.mark.filterwarnings("ignore:Setting a value on a view:FutureWarning")
     @pytest.mark.parametrize(
         "reader, module, path",
         [
diff --git a/pandas/tests/io/test_parquet.py b/pandas/tests/io/test_parquet.py
index 0a72fd7bbec7d..cd4075076062c 100644
--- a/pandas/tests/io/test_parquet.py
+++ b/pandas/tests/io/test_parquet.py
@@ -721,21 +721,15 @@ def test_basic_subset_columns(self, pa, df_full):
 
     def test_to_bytes_without_path_or_buf_provided(self, pa, df_full):
         # GH 37105
-        msg = "Mismatched null-like values nan and None found"
-        warn = None
-        if using_copy_on_write():
-            warn = FutureWarning
-
         buf_bytes = df_full.to_parquet(engine=pa)
         assert isinstance(buf_bytes, bytes)
 
         buf_stream = BytesIO(buf_bytes)
         res = read_parquet(buf_stream)
 
-        expected = df_full.copy(deep=False)
+        expected = df_full.copy()
         expected.loc[1, "string_with_nan"] = None
-        with tm.assert_produces_warning(warn, match=msg):
-            tm.assert_frame_equal(df_full, res)
+        tm.assert_frame_equal(res, expected)
 
     def test_duplicate_columns(self, pa):
         # not currently able to handle duplicate columns
diff --git a/pandas/tests/io/test_stata.py b/pandas/tests/io/test_stata.py
index c8ff42509505a..82e6c2964b8c5 100644
--- a/pandas/tests/io/test_stata.py
+++ b/pandas/tests/io/test_stata.py
@@ -32,6 +32,11 @@
     read_stata,
 )
 
+# TODO(CoW-warn) avoid warnings in the stata reader code
+pytestmark = pytest.mark.filterwarnings(
+    "ignore:Setting a value on a view:FutureWarning"
+)
+
 
 @pytest.fixture
 def mixed_frame():
@@ -178,11 +183,13 @@ def test_read_dta2(self, datapath):
         path2 = datapath("io", "data", "stata", "stata2_115.dta")
         path3 = datapath("io", "data", "stata", "stata2_117.dta")
 
-        with tm.assert_produces_warning(UserWarning):
+        # TODO(CoW-warn) avoid warnings in the stata reader code
+        # once fixed -> remove `raise_on_extra_warnings=False` again
+        with tm.assert_produces_warning(UserWarning, raise_on_extra_warnings=False):
             parsed_114 = self.read_dta(path1)
-        with tm.assert_produces_warning(UserWarning):
+        with tm.assert_produces_warning(UserWarning, raise_on_extra_warnings=False):
             parsed_115 = self.read_dta(path2)
-        with tm.assert_produces_warning(UserWarning):
+        with tm.assert_produces_warning(UserWarning, raise_on_extra_warnings=False):
             parsed_117 = self.read_dta(path3)
             # FIXME: don't leave commented-out
             # 113 is buggy due to limits of date format support in Stata