diff --git a/doc/source/whatsnew/v2.0.0.rst b/doc/source/whatsnew/v2.0.0.rst
index 252c444b2e60c..25fe1d3d541c0 100644
--- a/doc/source/whatsnew/v2.0.0.rst
+++ b/doc/source/whatsnew/v2.0.0.rst
@@ -141,6 +141,7 @@ Other API changes
 - The ``other`` argument in :meth:`DataFrame.mask` and :meth:`Series.mask` now defaults to ``no_default`` instead of ``np.nan`` consistent with :meth:`DataFrame.where` and :meth:`Series.where`. Entries will be filled with the corresponding NULL value (``np.nan`` for numpy dtypes, ``pd.NA`` for extension dtypes). (:issue:`49111`)
 - When creating a :class:`Series` with a object-dtype :class:`Index` of datetime objects, pandas no longer silently converts the index to a :class:`DatetimeIndex` (:issue:`39307`, :issue:`23598`)
 - :meth:`Series.unique` with dtype "timedelta64[ns]" or "datetime64[ns]" now returns :class:`TimedeltaArray` or :class:`DatetimeArray` instead of ``numpy.ndarray`` (:issue:`49176`)
+- Passing strings that cannot be parsed as datetimes to :class:`Series` or :class:`DataFrame` with ``dtype="datetime64[ns]"`` will raise instead of silently ignoring the keyword and returning ``object`` dtype (:issue:`24435`)
 -
 
 .. ---------------------------------------------------------------------------
diff --git a/pandas/core/dtypes/cast.py b/pandas/core/dtypes/cast.py
index 65112fc19ae56..54fa9629fecd4 100644
--- a/pandas/core/dtypes/cast.py
+++ b/pandas/core/dtypes/cast.py
@@ -20,7 +20,6 @@
 )
 import warnings
 
-from dateutil.parser import ParserError
 import numpy as np
 
 from pandas._libs import lib
@@ -1339,28 +1338,21 @@ def maybe_cast_to_datetime(
             if value.size or not is_dtype_equal(value.dtype, dtype):
                 _disallow_mismatched_datetimelike(value, dtype)
 
-                try:
-                    dta = sequence_to_datetimes(value)
-                    # GH 25843: Remove tz information since the dtype
-                    # didn't specify one
-
-                    if dta.tz is not None:
-                        raise ValueError(
-                            "Cannot convert timezone-aware data to "
-                            "timezone-naive dtype. Use "
-                            "pd.Series(values).dt.tz_localize(None) instead."
-                        )
-
-                    # TODO(2.0): Do this astype in sequence_to_datetimes to
-                    #  avoid potential extra copy?
-                    dta = dta.astype(dtype, copy=False)
-                    value = dta
-
-                except OutOfBoundsDatetime:
-                    raise
-                except ParserError:
-                    # Note: this is dateutil's ParserError, not ours.
-                    pass
+                dta = sequence_to_datetimes(value)
+                # GH 25843: Remove tz information since the dtype
+                # didn't specify one
+
+                if dta.tz is not None:
+                    raise ValueError(
+                        "Cannot convert timezone-aware data to "
+                        "timezone-naive dtype. Use "
+                        "pd.Series(values).dt.tz_localize(None) instead."
+                    )
+
+                # TODO(2.0): Do this astype in sequence_to_datetimes to
+                #  avoid potential extra copy?
+                dta = dta.astype(dtype, copy=False)
+                value = dta
 
         elif getattr(vdtype, "kind", None) in ["m", "M"]:
             # we are already datetimelike and want to coerce to non-datetimelike;
diff --git a/pandas/tests/frame/test_block_internals.py b/pandas/tests/frame/test_block_internals.py
index ed9d7bced9253..57e498defccc1 100644
--- a/pandas/tests/frame/test_block_internals.py
+++ b/pandas/tests/frame/test_block_internals.py
@@ -16,7 +16,6 @@
     DataFrame,
     Series,
     Timestamp,
-    compat,
     date_range,
     option_context,
 )
@@ -266,8 +265,8 @@ def f(dtype):
             f("float64")
 
         # 10822
-        # invalid error message on dt inference
-        if not compat.is_platform_windows():
+        msg = "Unknown string format: aa present at position 0"
+        with pytest.raises(ValueError, match=msg):
             f("M8[ns]")
 
     def test_pickle(self, float_string_frame, timezone_frame):
diff --git a/pandas/tests/series/test_constructors.py b/pandas/tests/series/test_constructors.py
index 9817c758759d5..c492f894d4f7c 100644
--- a/pandas/tests/series/test_constructors.py
+++ b/pandas/tests/series/test_constructors.py
@@ -52,6 +52,16 @@
 
 
 class TestSeriesConstructors:
+    def test_unparseable_strings_with_dt64_dtype(self):
+        # pre-2.0 these would be silently ignored and come back with object dtype
+        vals = ["aa"]
+        msg = "Unknown string format: aa present at position 0"
+        with pytest.raises(ValueError, match=msg):
+            Series(vals, dtype="datetime64[ns]")
+
+        with pytest.raises(ValueError, match=msg):
+            Series(np.array(vals, dtype=object), dtype="datetime64[ns]")
+
     @pytest.mark.parametrize(
         "constructor,check_index_type",
         [