diff --git a/doc/source/whatsnew/v2.0.0.rst b/doc/source/whatsnew/v2.0.0.rst
index 4ac737bb6b29a..01745ab0736d6 100644
--- a/doc/source/whatsnew/v2.0.0.rst
+++ b/doc/source/whatsnew/v2.0.0.rst
@@ -157,6 +157,7 @@ Removal of prior version deprecations/changes
 - Remove argument ``inplace`` from :meth:`MultiIndex.set_levels` and :meth:`MultiIndex.set_codes` (:issue:`35626`)
 - Disallow passing positional arguments to :meth:`MultiIndex.set_levels` and :meth:`MultiIndex.set_codes` (:issue:`41485`)
 - Removed argument ``try_cast`` from :meth:`DataFrame.mask`, :meth:`DataFrame.where`, :meth:`Series.mask` and :meth:`Series.where` (:issue:`38836`)
+- Removed argument ``is_copy`` from :meth:`DataFrame.take` and :meth:`Series.take` (:issue:`30615`)
 - Disallow passing non-round floats to :class:`Timestamp` with ``unit="M"`` or ``unit="Y"`` (:issue:`47266`)
 - Removed deprecated :meth:`Timedelta.delta`, :meth:`Timedelta.is_populated`, and :attr:`Timedelta.freq` (:issue:`46430`, :issue:`46476`)
 - Removed the ``numeric_only`` keyword from :meth:`Categorical.min` and :meth:`Categorical.max` in favor of ``skipna`` (:issue:`48821`)
diff --git a/pandas/core/generic.py b/pandas/core/generic.py
index a30b21d04ff59..5a554b417afe7 100644
--- a/pandas/core/generic.py
+++ b/pandas/core/generic.py
@@ -3794,9 +3794,7 @@ def _clear_item_cache(self) -> None:
     # ----------------------------------------------------------------------
     # Indexing Methods
 
-    def take(
-        self: NDFrameT, indices, axis: Axis = 0, is_copy: bool_t | None = None, **kwargs
-    ) -> NDFrameT:
+    def take(self: NDFrameT, indices, axis: Axis = 0, **kwargs) -> NDFrameT:
         """
         Return the elements in the given *positional* indices along an axis.
 
@@ -3812,13 +3810,6 @@ def take(
             The axis on which to select elements. ``0`` means that we are
             selecting rows, ``1`` means that we are selecting columns.
             For `Series` this parameter is unused and defaults to 0.
-        is_copy : bool
-            Before pandas 1.0, ``is_copy=False`` can be specified to ensure
-            that the return value is an actual copy. Starting with pandas 1.0,
-            ``take`` always returns a copy, and the keyword is therefore
-            deprecated.
-
-            .. deprecated:: 1.0.0
         **kwargs
             For compatibility with :meth:`numpy.take`. Has no effect on the
             output.
@@ -3877,13 +3868,6 @@ class  max_speed
         1  monkey  mammal        NaN
         3    lion  mammal       80.5
         """
-        if is_copy is not None:
-            warnings.warn(
-                "is_copy is deprecated and will be removed in a future version. "
-                "'take' always returns a copy, so there is no need to specify this.",
-                FutureWarning,
-                stacklevel=find_stack_level(),
-            )
 
         nv.validate_take((), kwargs)
 
diff --git a/pandas/core/groupby/generic.py b/pandas/core/groupby/generic.py
index 2bac228ef74a0..47452d885543e 100644
--- a/pandas/core/groupby/generic.py
+++ b/pandas/core/groupby/generic.py
@@ -856,12 +856,9 @@ def take(
         self,
         indices: TakeIndexer,
         axis: Axis = 0,
-        is_copy: bool | None = None,
         **kwargs,
     ) -> Series:
-        result = self._op_via_apply(
-            "take", indices=indices, axis=axis, is_copy=is_copy, **kwargs
-        )
+        result = self._op_via_apply("take", indices=indices, axis=axis, **kwargs)
         return result
 
     @doc(Series.skew.__doc__)
@@ -2254,12 +2251,9 @@ def take(
         self,
         indices: TakeIndexer,
         axis: Axis | None = 0,
-        is_copy: bool | None = None,
         **kwargs,
     ) -> DataFrame:
-        result = self._op_via_apply(
-            "take", indices=indices, axis=axis, is_copy=is_copy, **kwargs
-        )
+        result = self._op_via_apply("take", indices=indices, axis=axis, **kwargs)
         return result
 
     @doc(DataFrame.skew.__doc__)
diff --git a/pandas/core/series.py b/pandas/core/series.py
index bf062ec53eec1..b7d12158fd909 100644
--- a/pandas/core/series.py
+++ b/pandas/core/series.py
@@ -889,16 +889,7 @@ def axes(self) -> list[Index]:
     # Indexing Methods
 
     @Appender(NDFrame.take.__doc__)
-    def take(
-        self, indices, axis: Axis = 0, is_copy: bool | None = None, **kwargs
-    ) -> Series:
-        if is_copy is not None:
-            warnings.warn(
-                "is_copy is deprecated and will be removed in a future version. "
-                "'take' always returns a copy, so there is no need to specify this.",
-                FutureWarning,
-                stacklevel=find_stack_level(),
-            )
+    def take(self, indices, axis: Axis = 0, **kwargs) -> Series:
         nv.validate_take((), kwargs)
 
         indices = ensure_platform_int(indices)
diff --git a/pandas/tests/generic/test_generic.py b/pandas/tests/generic/test_generic.py
index 80d9bde784018..a6c516b51c6c5 100644
--- a/pandas/tests/generic/test_generic.py
+++ b/pandas/tests/generic/test_generic.py
@@ -429,21 +429,6 @@ def test_take_invalid_kwargs(self, frame_or_series):
         with pytest.raises(ValueError, match=msg):
             obj.take(indices, mode="clip")
 
-    @pytest.mark.parametrize("is_copy", [True, False])
-    def test_depr_take_kwarg_is_copy(self, is_copy, frame_or_series):
-        # GH 27357
-        obj = DataFrame({"A": [1, 2, 3]})
-        obj = tm.get_obj(obj, frame_or_series)
-
-        msg = (
-            "is_copy is deprecated and will be removed in a future version. "
-            "'take' always returns a copy, so there is no need to specify this."
-        )
-        with tm.assert_produces_warning(FutureWarning) as w:
-            obj.take([0, 1], is_copy=is_copy)
-
-        assert w[0].message.args[0] == msg
-
     def test_axis_classmethods(self, frame_or_series):
         box = frame_or_series
         obj = box(dtype=object)