diff --git a/doc/source/whatsnew/v1.6.0.rst b/doc/source/whatsnew/v1.6.0.rst
index a7c9a7eb88221..7c07d3112be3c 100644
--- a/doc/source/whatsnew/v1.6.0.rst
+++ b/doc/source/whatsnew/v1.6.0.rst
@@ -196,6 +196,7 @@ Plotting
 Groupby/resample/rolling
 ^^^^^^^^^^^^^^^^^^^^^^^^
 - Bug in :meth:`DataFrameGroupBy.sample` raises ``ValueError`` when the object is empty (:issue:`48459`)
+- Bug in :meth:`Series.groupby` raises ``ValueError`` when an entry of the index is equal to the name of the index (:issue:`48567`)
 -
 
 Reshaping
diff --git a/pandas/core/groupby/grouper.py b/pandas/core/groupby/grouper.py
index 5fc713d84e842..8d52f34b8d825 100644
--- a/pandas/core/groupby/grouper.py
+++ b/pandas/core/groupby/grouper.py
@@ -875,7 +875,7 @@ def is_in_obj(gpr) -> bool:
             exclusions.add(gpr.name)
 
         elif is_in_axis(gpr):  # df.groupby('name')
-            if gpr in obj:
+            if obj.ndim != 1 and gpr in obj:
                 if validate:
                     obj._check_label_or_level_ambiguity(gpr, axis=axis)
                 in_axis, name, gpr = True, gpr, obj[gpr]
diff --git a/pandas/tests/groupby/test_groupby.py b/pandas/tests/groupby/test_groupby.py
index ba39f76203623..b6c159f67582c 100644
--- a/pandas/tests/groupby/test_groupby.py
+++ b/pandas/tests/groupby/test_groupby.py
@@ -2907,3 +2907,34 @@ def test_groupby_cumsum_mask(any_numeric_ea_dtype, skipna, val):
         dtype=any_numeric_ea_dtype,
     )
     tm.assert_frame_equal(result, expected)
+
+
+@pytest.mark.parametrize(
+    "val_in, index, val_out",
+    [
+        (
+            [1.0, 2.0, 3.0, 4.0, 5.0],
+            ["foo", "foo", "bar", "baz", "blah"],
+            [3.0, 4.0, 5.0, 3.0],
+        ),
+        (
+            [1.0, 2.0, 3.0, 4.0, 5.0, 6.0],
+            ["foo", "foo", "bar", "baz", "blah", "blah"],
+            [3.0, 4.0, 11.0, 3.0],
+        ),
+    ],
+)
+def test_groupby_index_name_in_index_content(val_in, index, val_out):
+    # GH 48567
+    series = Series(data=val_in, name="values", index=Index(index, name="blah"))
+    result = series.groupby("blah").sum()
+    expected = Series(
+        data=val_out,
+        name="values",
+        index=Index(["bar", "baz", "blah", "foo"], name="blah"),
+    )
+    tm.assert_series_equal(result, expected)
+
+    result = series.to_frame().groupby("blah").sum()
+    expected = expected.to_frame()
+    tm.assert_frame_equal(result, expected)