diff --git a/doc/source/whatsnew/v1.6.0.rst b/doc/source/whatsnew/v1.6.0.rst
index 098750aa3a2b2..6e435c8eaaf2f 100644
--- a/doc/source/whatsnew/v1.6.0.rst
+++ b/doc/source/whatsnew/v1.6.0.rst
@@ -244,6 +244,7 @@ Groupby/resample/rolling
 - Bug in :class:`.ExponentialMovingWindow` with ``online`` not raising a ``NotImplementedError`` for unsupported operations (:issue:`48834`)
 - Bug in :meth:`DataFrameGroupBy.sample` raises ``ValueError`` when the object is empty (:issue:`48459`)
 - Bug in :meth:`Series.groupby` raises ``ValueError`` when an entry of the index is equal to the name of the index (:issue:`48567`)
+- Bug in :meth:`DataFrameGroupBy.resample` produces inconsistent results when passing empty DataFrame (:issue:`47705`)
 -
 
 Reshaping
diff --git a/pandas/core/resample.py b/pandas/core/resample.py
index 0cf1aafed0f56..574c2e5e0f552 100644
--- a/pandas/core/resample.py
+++ b/pandas/core/resample.py
@@ -522,11 +522,21 @@ def _wrap_result(self, result):
         """
         Potentially wrap any results.
         """
+        # GH 47705
+        obj = self.obj
+        if (
+            isinstance(result, ABCDataFrame)
+            and result.empty
+            and not isinstance(result.index, PeriodIndex)
+        ):
+            result = result.set_index(
+                _asfreq_compat(obj.index[:0], freq=self.freq), append=True
+            )
+
         if isinstance(result, ABCSeries) and self._selection is not None:
             result.name = self._selection
 
         if isinstance(result, ABCSeries) and result.empty:
-            obj = self.obj
             # When index is all NaT, result is empty but index is not
             result.index = _asfreq_compat(obj.index[:0], freq=self.freq)
             result.name = getattr(obj, "name", None)
diff --git a/pandas/tests/resample/test_resampler_grouper.py b/pandas/tests/resample/test_resampler_grouper.py
index ceb9d6e2fda4d..7fe1e645aa141 100644
--- a/pandas/tests/resample/test_resampler_grouper.py
+++ b/pandas/tests/resample/test_resampler_grouper.py
@@ -435,7 +435,11 @@ def test_empty(keys):
     # GH 26411
     df = DataFrame([], columns=["a", "b"], index=TimedeltaIndex([]))
     result = df.groupby(keys).resample(rule=pd.to_timedelta("00:00:01")).mean()
-    expected = DataFrame(columns=["a", "b"]).set_index(keys, drop=False)
+    expected = (
+        DataFrame(columns=["a", "b"])
+        .set_index(keys, drop=False)
+        .set_index(TimedeltaIndex([]), append=True)
+    )
     if len(keys) == 1:
         expected.index.name = keys[0]
 
@@ -497,3 +501,19 @@ def test_groupby_resample_with_list_of_keys():
         ),
     )
     tm.assert_frame_equal(result, expected)
+
+
+@pytest.mark.parametrize("keys", [["a"], ["a", "b"]])
+def test_resample_empty_Dataframe(keys):
+    # GH 47705
+    df = DataFrame([], columns=["a", "b", "date"])
+    df["date"] = pd.to_datetime(df["date"])
+    df = df.set_index("date")
+    result = df.groupby(keys).resample(rule=pd.to_timedelta("00:00:01")).mean()
+    expected = DataFrame(columns=["a", "b", "date"]).set_index(keys, drop=False)
+    expected["date"] = pd.to_datetime(expected["date"])
+    expected = expected.set_index("date", append=True, drop=True)
+    if len(keys) == 1:
+        expected.index.name = keys[0]
+
+    tm.assert_frame_equal(result, expected)