diff --git a/.github/workflows/posix.yml b/.github/workflows/posix.yml
index 135ca0703de8b..1cc8188919980 100644
--- a/.github/workflows/posix.yml
+++ b/.github/workflows/posix.yml
@@ -35,7 +35,7 @@ jobs:
           [actions-pypy-38.yaml, "not slow and not clipboard", "", "", "", "", "--max-worker-restart 0"],
           [actions-39.yaml, "slow", "", "", "", "", ""],
           [actions-39.yaml, "not slow and not clipboard", "", "", "", "", ""],
-          [actions-310-numpydev.yaml, "not slow and not network", "xclip", "", "", "deprecate", "-W error"],
+          [actions-310-numpydev.yaml, "not slow and not network", "xsel", "", "", "deprecate", "-W error"],
           [actions-310.yaml, "not slow and not clipboard", "", "", "", "", ""],
           [actions-310.yaml, "slow", "", "", "", "", ""],
         ]
diff --git a/pandas/tests/io/test_clipboard.py b/pandas/tests/io/test_clipboard.py
index 40b2eb1f4114b..4a53705193e99 100644
--- a/pandas/tests/io/test_clipboard.py
+++ b/pandas/tests/io/test_clipboard.py
@@ -307,6 +307,11 @@ def test_round_trip_valid_encodings(self, enc, df):
 @pytest.mark.single
 @pytest.mark.clipboard
 @pytest.mark.parametrize("data", ["\U0001f44d...", "Ωœ∑´...", "abcd..."])
+@pytest.mark.xfail(
+    reason="Flaky test in multi-process CI environment: GH 44584",
+    raises=AssertionError,
+    strict=False,
+)
 def test_raw_roundtrip(data):
     # PR #25040 wide unicode wasn't copied correctly on PY3 on windows
     clipboard_set(data)