diff --git a/.github/workflows/asv-bot.yml b/.github/workflows/asv-bot.yml
new file mode 100644
index 0000000000000..c2a49dd96c1c1
--- /dev/null
+++ b/.github/workflows/asv-bot.yml
@@ -0,0 +1,81 @@
+name: "ASV Bot"
+
+on:
+  issue_comment: # Pull requests are issues
+    types:
+      - created
+
+env:
+  ENV_FILE: environment.yml
+  COMMENT: ${{github.event.comment.body}}
+
+jobs:
+  autotune:
+    name: "Run benchmarks"
+    # TODO: Support more benchmarking options later, against different branches, against self, etc
+    if: startsWith(github.event.comment.body, '@github-actions benchmark')
+    runs-on: ubuntu-latest
+    defaults:
+      run:
+        shell: bash -l {0}
+
+    concurrency:
+      # Set concurrency to prevent abuse(full runs are ~5.5 hours !!!)
+      # each user can only run one concurrent benchmark bot at a time
+      # We don't cancel in progress jobs, but if you want to benchmark multiple PRs, you're gonna have
+      # to wait
+      group: ${{ github.actor }}-asv
+      cancel-in-progress: false
+
+    steps:
+      - name: Checkout
+        uses: actions/checkout@v2
+        with:
+          fetch-depth: 0
+
+      - name: Cache conda
+        uses: actions/cache@v2
+        with:
+          path: ~/conda_pkgs_dir
+          key: ${{ runner.os }}-conda-${{ hashFiles('${{ env.ENV_FILE }}') }}
+
+        # Although asv sets up its own env, deps are still needed
+        # during discovery process
+      - uses: conda-incubator/setup-miniconda@v2
+        with:
+          activate-environment: pandas-dev
+          channel-priority: strict
+          environment-file: ${{ env.ENV_FILE }}
+          use-only-tar-bz2: true
+
+      - name: Run benchmarks
+        id: bench
+        continue-on-error: true # This is a fake failure, asv will exit code 1 for regressions
+        run: |
+          # extracting the regex, see https://stackoverflow.com/a/36798723
+          REGEX=$(echo "$COMMENT" | sed -n "s/^.*-b\s*\(\S*\).*$/\1/p")
+          cd asv_bench
+          asv check -E existing
+          git remote add upstream https://github.com/pandas-dev/pandas.git
+          git fetch upstream
+          asv machine --yes
+          asv continuous -f 1.1 -b $REGEX upstream/master HEAD
+          echo 'BENCH_OUTPUT<<EOF' >> $GITHUB_ENV
+          asv compare -f 1.1 upstream/master HEAD >> $GITHUB_ENV
+          echo 'EOF' >> $GITHUB_ENV
+          echo "REGEX=$REGEX" >> $GITHUB_ENV
+
+      - uses: actions/github-script@v4
+        env:
+          BENCH_OUTPUT: ${{env.BENCH_OUTPUT}}
+          REGEX: ${{env.REGEX}}
+        with:
+          script: |
+            const ENV_VARS = process.env
+            const run_url = `https://github.com/${context.repo.owner}/${context.repo.repo}/actions/runs/${context.runId}`
+            github.issues.createComment({
+              issue_number: context.issue.number,
+              owner: context.repo.owner,
+              repo: context.repo.repo,
+              body: '\nBenchmarks completed. View runner logs here.' + run_url + '\nRegex used: '+ 'regex ' + ENV_VARS["REGEX"] + '\n' + ENV_VARS["BENCH_OUTPUT"]
+            })