diff --git a/.github/workflows/pre-commit.yml b/.github/workflows/pre-commit.yml
new file mode 100644
index 0000000000000..723347913ac38
--- /dev/null
+++ b/.github/workflows/pre-commit.yml
@@ -0,0 +1,14 @@
+name: pre-commit
+
+on:
+  pull_request:
+  push:
+    branches: [master]
+
+jobs:
+  pre-commit:
+    runs-on: ubuntu-latest
+    steps:
+    - uses: actions/checkout@v2
+    - uses: actions/setup-python@v2
+    - uses: pre-commit/action@v2.0.0
diff --git a/.pre-commit-config.yaml b/.pre-commit-config.yaml
index 309e22e71a523..2fa5f5ec5d4fa 100644
--- a/.pre-commit-config.yaml
+++ b/.pre-commit-config.yaml
@@ -3,30 +3,30 @@ repos:
     rev: 19.10b0
     hooks:
     -   id: black
-        language_version: python3
 -   repo: https://gitlab.com/pycqa/flake8
     rev: 3.8.3
     hooks:
     -   id: flake8
-        language: python_venv
         additional_dependencies: [flake8-comprehensions>=3.1.0]
     -   id: flake8
         name: flake8-pyx
-        language: python_venv
         files: \.(pyx|pxd)$
         types:
           - file
         args: [--append-config=flake8/cython.cfg]
     -   id: flake8
         name: flake8-pxd
-        language: python_venv
         files: \.pxi\.in$
         types:
           - file
         args: [--append-config=flake8/cython-template.cfg]
--   repo: https://github.com/pre-commit/mirrors-isort
-    rev: v5.2.2
+-   repo: https://github.com/PyCQA/isort
+    rev: 5.2.2
     hooks:
     -   id: isort
-        language: python_venv
         exclude: ^pandas/__init__\.py$|^pandas/core/api\.py$
+-   repo: https://github.com/asottile/pyupgrade
+    rev: v2.7.2
+    hooks:
+    -   id: pyupgrade
+        args: [--py37-plus]
diff --git a/doc/source/development/contributing.rst b/doc/source/development/contributing.rst
index e5c6f77eea3ef..6f29ea8b764bd 100644
--- a/doc/source/development/contributing.rst
+++ b/doc/source/development/contributing.rst
@@ -634,6 +634,10 @@ do not make sudden changes to the code that could have the potential to break
 a lot of user code as a result, that is, we need it to be as *backwards compatible*
 as possible to avoid mass breakages.
 
+In addition to ``./ci/code_checks.sh``, some extra checks are run by
+``pre-commit`` - see :ref:`here <contributing.pre-commit>` for how to
+run them.
+
 Additional standards are outlined on the :ref:`pandas code style guide <code_style>`
 
 Optional dependencies
@@ -826,6 +830,13 @@ remain up-to-date with our code checks as they change.
 
 Note that if needed, you can skip these checks with ``git commit --no-verify``.
 
+If you don't want to use ``pre-commit`` as part of your workflow, you can still use it
+to run its checks by running::
+
+    pre-commit run --files <files you have modified>
+
+without having to have done ``pre-commit install`` beforehand.
+
 Backwards compatibility
 ~~~~~~~~~~~~~~~~~~~~~~~
 
diff --git a/doc/sphinxext/announce.py b/doc/sphinxext/announce.py
index 9c175e4e58b45..2ec0b515ea95c 100755
--- a/doc/sphinxext/announce.py
+++ b/doc/sphinxext/announce.py
@@ -1,5 +1,4 @@
 #!/usr/bin/env python3
-# -*- encoding:utf-8 -*-
 """
 Script to generate contributor and pull request lists
 
diff --git a/environment.yml b/environment.yml
index 36bbd3d307159..1a260b0f7cc56 100644
--- a/environment.yml
+++ b/environment.yml
@@ -22,7 +22,9 @@ dependencies:
   - flake8-rst>=0.6.0,<=0.7.0  # linting of code blocks in rst files
   - isort>=5.2.1  # check that imports are in the right order
   - mypy=0.782
+  - pre-commit
   - pycodestyle  # used by flake8
+  - pyupgrade
 
   # documentation
   - gitpython  # obtain contributors from git for whatsnew
diff --git a/requirements-dev.txt b/requirements-dev.txt
index fb647c10f72bc..9ee26562e6d4b 100644
--- a/requirements-dev.txt
+++ b/requirements-dev.txt
@@ -13,7 +13,9 @@ flake8-comprehensions>=3.1.0
 flake8-rst>=0.6.0,<=0.7.0
 isort>=5.2.1
 mypy==0.782
+pre-commit
 pycodestyle
+pyupgrade
 gitpython
 gitdb
 sphinx