diff --git a/doc/source/getting_started/install.rst b/doc/source/getting_started/install.rst
index b5c512cdc8328..8f5900a2a1ba6 100644
--- a/doc/source/getting_started/install.rst
+++ b/doc/source/getting_started/install.rst
@@ -264,7 +264,7 @@ pyarrow                   0.12.0             Parquet, ORC (requires 0.13.0), and
 pymysql                   0.7.11             MySQL engine for sqlalchemy
 pyreadstat                                   SPSS files (.sav) reading
 pytables                  3.4.2              HDF5 reading / writing
-pyxlsb                    1.0.5              Reading for xlsb files
+pyxlsb                    1.0.6              Reading for xlsb files
 qtpy                                         Clipboard I/O
 s3fs                      0.3.0              Amazon S3 access
 tabulate                  0.8.3              Printing in Markdown-friendly format (see `tabulate`_)
diff --git a/pandas/compat/_optional.py b/pandas/compat/_optional.py
index d561ab9a10548..cd711bcace013 100644
--- a/pandas/compat/_optional.py
+++ b/pandas/compat/_optional.py
@@ -19,7 +19,7 @@
     "pyarrow": "0.13.0",
     "pytables": "3.4.2",
     "pytest": "5.0.1",
-    "pyxlsb": "1.0.5",
+    "pyxlsb": "1.0.6",
     "s3fs": "0.3.0",
     "scipy": "0.19.0",
     "sqlalchemy": "1.1.4",
diff --git a/pandas/tests/io/excel/test_readers.py b/pandas/tests/io/excel/test_readers.py
index f8ff3567b8b64..8d00ef1b7fe3e 100644
--- a/pandas/tests/io/excel/test_readers.py
+++ b/pandas/tests/io/excel/test_readers.py
@@ -562,11 +562,6 @@ def test_bad_engine_raises(self, read_ext):
 
     @tm.network
     def test_read_from_http_url(self, read_ext):
-        if read_ext == ".xlsb":
-            pytest.xfail("xlsb files not present in master repo yet")
-        if pd.read_excel.keywords["engine"] == "pyxlsb":
-            pytest.xfail("Sheets containing datetimes not supported by pyxlsb")
-
         url = (
             "https://raw.githubusercontent.com/pandas-dev/pandas/master/"
             "pandas/tests/io/data/excel/test1" + read_ext