diff --git a/pandas/tests/indexes/interval/test_interval_tree.py b/pandas/tests/indexes/interval/test_interval_tree.py
index 46b2d12015a22..5d9ef2a9a6c32 100644
--- a/pandas/tests/indexes/interval/test_interval_tree.py
+++ b/pandas/tests/indexes/interval/test_interval_tree.py
@@ -172,6 +172,7 @@ def test_is_overlapping_trivial(self, closed, left, right):
         tree = IntervalTree(left, right, closed=closed)
         assert tree.is_overlapping is False
 
+    @pytest.mark.skipif(compat.is_platform_32bit(), reason='GH 23440')
     def test_construction_overflow(self):
         # GH 25485
         left, right = np.arange(101), [np.iinfo(np.int64).max] * 101