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- Enforced :meth:`Rolling.count` with ``min_periods=None`` to default to the size of the window (:issue:`31302`)
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- Renamed ``fname`` to ``path`` in :meth:`DataFrame.to_parquet`, :meth:`DataFrame.to_stata` and :meth:`DataFrame.to_feather` (:issue:`30338`)
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- Enforced disallowing indexing a :class:`Series` with a single item list with a slice (e.g. ``ser[[slice(0, 2)]]``). Either convert the list to tuple, or pass the slice directly instead (:issue:`31333`)
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- Enforced the ``display.max_colwidth`` option to not accept negative integers (:issue:`31569`)
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- Removed the ``display.column_space`` option in favor of ``df.to_string(col_space=...)`` (:issue:`47280`)
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- Removed the deprecated method ``mad`` from pandas classes (:issue:`11787`)
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- Removed the deprecated method ``tshift`` from pandas classes (:issue:`11631`)
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- Changed the behavior of :func:`to_datetime` with argument "now" with ``utc=False`` to match ``Timestamp("now")`` (:issue:`18705`)
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- Changed behavior of :class:`DataFrame` constructor given floating-point ``data`` and an integer ``dtype``, when the data cannot be cast losslessly, the floating point dtype is retained, matching :class:`Series` behavior (:issue:`41170`)
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- Changed behavior of :class:`DataFrame` constructor when passed a ``dtype`` (other than int) that the data cannot be cast to; it now raises instead of silently ignoring the dtype (:issue:`41733`)
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- Changed the behavior of :class:`Series` constructor, it will no longer infer a datetime64 or timedelta64 dtype from string entries (:issue:`41731`)
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- Changed behavior of :class:`Index` constructor when passed a ``SparseArray`` or ``SparseDtype`` to retain that dtype instead of casting to ``numpy.ndarray`` (:issue:`43930`)
- Bug in :meth:`Series.convert_dtypes` not converting dtype to nullable dtype when :class:`Series` contains ``NA`` and has dtype ``object`` (:issue:`48791`)
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- Bug where any :class:`ExtensionDtype` subclass with ``kind="M"`` would be interpreted as a timezone type (:issue:`34986`)
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- Bug in :class:`.arrays.ArrowExtensionArray` that would raise ``NotImplementedError`` when passed a sequence of strings or binary (:issue:`49172`)
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- Bug in :func:`to_datetime` was not respecting ``exact`` argument when ``format`` was an ISO8601 format (:issue:`12649`)
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