diff --git a/pandas-stubs/core/frame.pyi b/pandas-stubs/core/frame.pyi
index a081d5c09..482a2dcc3 100644
--- a/pandas-stubs/core/frame.pyi
+++ b/pandas-stubs/core/frame.pyi
@@ -89,7 +89,10 @@ class _iLocIndexerFrame(_iLocIndexer):
     @overload
     def __getitem__(
         self,
-        idx: IndexType | MaskType | tuple[IndexType | MaskType, IndexType | MaskType],
+        idx: IndexType
+        | MaskType
+        | tuple[IndexType | MaskType, IndexType | MaskType]
+        | tuple[slice],
     ) -> DataFrame: ...
     def __setitem__(
         self,
diff --git a/tests/test_frame.py b/tests/test_frame.py
index 27ced9263..9bd211d70 100644
--- a/tests/test_frame.py
+++ b/tests/test_frame.py
@@ -1152,6 +1152,14 @@ def test_iloc_npint() -> None:
     df.iloc[iloc]
 
 
+# https://github.com/pandas-dev/pandas-stubs/issues/143
+def test_iloc_tuple() -> None:
+    df = pd.DataFrame({"Char": ["A", "B", "C"], "Number": [1, 2, 3]})
+    df = df.iloc[
+        0:2,
+    ]
+
+
 def test_set_columns() -> None:
     # GH 73
     df = pd.DataFrame({"a": [1, 2, 3], "b": [0.0, 1, 1]})