diff --git a/src/sagemaker/clarify.py b/src/sagemaker/clarify.py
index e22a82b431..5d36eb229d 100644
--- a/src/sagemaker/clarify.py
+++ b/src/sagemaker/clarify.py
@@ -723,8 +723,10 @@ def run_explainability(
                 endpoint to be created.
             explainability_config (:class:`~sagemaker.clarify.ExplainabilityConfig`): Config of the
                 specific explainability method. Currently, only SHAP is supported.
-            model_scores:  Index or JSONPath location in the model output for the predicted scores
-                to be explained. This is not required if the model output is a single score.
+            model_scores(str|int|ModelPredictedLabelConfig):  Index or JSONPath location in the
+                model output for the predicted scores to be explained. This is not required if the
+                model output is a single score. Alternatively, an instance of
+                ModelPredictedLabelConfig can be provided.
             wait (bool): Whether the call should wait until the job completes (default: True).
             logs (bool): Whether to show the logs produced by the job.
                 Only meaningful when ``wait`` is True (default: True).
@@ -740,7 +742,12 @@ def run_explainability(
         """
         analysis_config = data_config.get_config()
         predictor_config = model_config.get_predictor_config()
-        _set(model_scores, "label", predictor_config)
+        if isinstance(model_scores, ModelPredictedLabelConfig):
+            probability_threshold, predicted_label_config = model_scores.get_predictor_config()
+            _set(probability_threshold, "probability_threshold", analysis_config)
+            predictor_config.update(predicted_label_config)
+        else:
+            _set(model_scores, "label", predictor_config)
         analysis_config["methods"] = explainability_config.get_explainability_config()
         analysis_config["predictor"] = predictor_config
         if job_name is None:
diff --git a/tests/unit/test_clarify.py b/tests/unit/test_clarify.py
index 9cf17bcf09..7c6ae7e8c9 100644
--- a/tests/unit/test_clarify.py
+++ b/tests/unit/test_clarify.py
@@ -442,21 +442,22 @@ def test_post_training_bias(
         )
 
 
-@patch("sagemaker.utils.name_from_base", return_value=JOB_NAME)
-def test_shap(
+def _run_test_shap(
     name_from_base,
     clarify_processor,
     clarify_processor_with_job_name_prefix,
     data_config,
     model_config,
     shap_config,
+    model_scores,
+    expected_predictor_config,
 ):
     with patch.object(SageMakerClarifyProcessor, "_run", return_value=None) as mock_method:
         clarify_processor.run_explainability(
             data_config,
             model_config,
             shap_config,
-            model_scores=None,
+            model_scores=model_scores,
             wait=True,
             job_name="test",
             experiment_config={"ExperimentName": "AnExperiment"},
@@ -485,11 +486,7 @@ def test_shap(
                     "save_local_shap_values": True,
                 }
             },
-            "predictor": {
-                "model_name": "xgboost-model",
-                "instance_type": "ml.c5.xlarge",
-                "initial_instance_count": 1,
-            },
+            "predictor": expected_predictor_config,
         }
         mock_method.assert_called_with(
             data_config,
@@ -504,7 +501,7 @@ def test_shap(
             data_config,
             model_config,
             shap_config,
-            model_scores=None,
+            model_scores=model_scores,
             wait=True,
             experiment_config={"ExperimentName": "AnExperiment"},
         )
@@ -518,3 +515,63 @@ def test_shap(
             None,
             {"ExperimentName": "AnExperiment"},
         )
+
+
+@patch("sagemaker.utils.name_from_base", return_value=JOB_NAME)
+def test_shap(
+    name_from_base,
+    clarify_processor,
+    clarify_processor_with_job_name_prefix,
+    data_config,
+    model_config,
+    shap_config,
+):
+    expected_predictor_config = {
+        "model_name": "xgboost-model",
+        "instance_type": "ml.c5.xlarge",
+        "initial_instance_count": 1,
+    }
+    _run_test_shap(
+        name_from_base,
+        clarify_processor,
+        clarify_processor_with_job_name_prefix,
+        data_config,
+        model_config,
+        shap_config,
+        None,
+        expected_predictor_config,
+    )
+
+
+@patch("sagemaker.utils.name_from_base", return_value=JOB_NAME)
+def test_shap_with_predicted_label(
+    name_from_base,
+    clarify_processor,
+    clarify_processor_with_job_name_prefix,
+    data_config,
+    model_config,
+    shap_config,
+):
+    probability = "pr"
+    label_headers = ["success"]
+    model_scores = ModelPredictedLabelConfig(
+        probability=probability,
+        label_headers=label_headers,
+    )
+    expected_predictor_config = {
+        "model_name": "xgboost-model",
+        "instance_type": "ml.c5.xlarge",
+        "initial_instance_count": 1,
+        "probability": probability,
+        "label_headers": label_headers,
+    }
+    _run_test_shap(
+        name_from_base,
+        clarify_processor,
+        clarify_processor_with_job_name_prefix,
+        data_config,
+        model_config,
+        shap_config,
+        model_scores,
+        expected_predictor_config,
+    )