diff --git a/README.rst b/README.rst
index 7f1b22824..b9acc3edc 100644
--- a/README.rst
+++ b/README.rst
@@ -34,7 +34,7 @@ Getting Started
 Required Prerequisites
 ======================
 
-* Python 3.6+
+* Python 3.7+
 * cryptography >= 2.5.0
 * boto3 >= 1.10.0
 * attrs
diff --git a/buildspec.yml b/buildspec.yml
index 5d50f5675..2f2571f64 100644
--- a/buildspec.yml
+++ b/buildspec.yml
@@ -3,11 +3,6 @@ version: 0.2
 batch:
   fast-fail: false
   build-list:
-    - identifier: py36_integ
-      buildspec: codebuild/py36/integ.yml
-    - identifier: py36_examples
-      buildspec: codebuild/py36/examples.yml
-
     - identifier: py37_integ
       buildspec: codebuild/py37/integ.yml
     - identifier: py37_examples
diff --git a/codebuild/py36/examples.yml b/codebuild/py36/examples.yml
deleted file mode 100644
index 46af14902..000000000
--- a/codebuild/py36/examples.yml
+++ /dev/null
@@ -1,24 +0,0 @@
-version: 0.2
-
-env:
-  variables:
-    TOXENV: "py36-examples"
-    AWS_ENCRYPTION_SDK_PYTHON_INTEGRATION_TEST_AWS_KMS_KEY_ID: >-
-      arn:aws:kms:us-west-2:658956600833:key/b3537ef1-d8dc-4780-9f5a-55776cbb2f7f
-    AWS_ENCRYPTION_SDK_PYTHON_INTEGRATION_TEST_AWS_KMS_KEY_ID_2: >-
-      arn:aws:kms:eu-central-1:658956600833:key/75414c93-5285-4b57-99c9-30c1cf0a22c2
-    AWS_ENCRYPTION_SDK_PYTHON_INTEGRATION_TEST_AWS_KMS_MRK_KEY_ID_1: >-
-      arn:aws:kms:us-west-2:658956600833:key/mrk-80bd8ecdcd4342aebd84b7dc9da498a7
-    AWS_ENCRYPTION_SDK_PYTHON_INTEGRATION_TEST_AWS_KMS_MRK_KEY_ID_2: >-
-      arn:aws:kms:us-east-1:658956600833:key/mrk-80bd8ecdcd4342aebd84b7dc9da498a7
-
-phases:
-  install:
-    runtime-versions:
-      python: latest
-  build:
-    commands:
-      - pyenv install 3.6.15
-      - pyenv local 3.6.15
-      - pip install tox tox-pyenv
-      - tox
diff --git a/codebuild/py36/integ.yml b/codebuild/py36/integ.yml
deleted file mode 100644
index d55581c43..000000000
--- a/codebuild/py36/integ.yml
+++ /dev/null
@@ -1,24 +0,0 @@
-version: 0.2
-
-env:
-  variables:
-    TOXENV: "py36-integ"
-    AWS_ENCRYPTION_SDK_PYTHON_INTEGRATION_TEST_AWS_KMS_KEY_ID: >-
-      arn:aws:kms:us-west-2:658956600833:key/b3537ef1-d8dc-4780-9f5a-55776cbb2f7f
-    AWS_ENCRYPTION_SDK_PYTHON_INTEGRATION_TEST_AWS_KMS_KEY_ID_2: >-
-      arn:aws:kms:eu-central-1:658956600833:key/75414c93-5285-4b57-99c9-30c1cf0a22c2
-    AWS_ENCRYPTION_SDK_PYTHON_INTEGRATION_TEST_AWS_KMS_MRK_KEY_ID_1: >-
-      arn:aws:kms:us-west-2:658956600833:key/mrk-80bd8ecdcd4342aebd84b7dc9da498a7
-    AWS_ENCRYPTION_SDK_PYTHON_INTEGRATION_TEST_AWS_KMS_MRK_KEY_ID_2: >-
-      arn:aws:kms:us-east-1:658956600833:key/mrk-80bd8ecdcd4342aebd84b7dc9da498a7
-
-phases:
-  install:
-    runtime-versions:
-      python: latest
-  build:
-    commands:
-      - pyenv install 3.6.15
-      - pyenv local 3.6.15
-      - pip install tox tox-pyenv
-      - tox
diff --git a/setup.py b/setup.py
index 2db856d89..7cc111bac 100644
--- a/setup.py
+++ b/setup.py
@@ -46,7 +46,6 @@ def get_requirements():
         "License :: OSI Approved :: Apache Software License",
         "Programming Language :: Python",
         "Programming Language :: Python :: 3",
-        "Programming Language :: Python :: 3.6",
         "Programming Language :: Python :: 3.7",
         "Programming Language :: Python :: 3.8",
         "Programming Language :: Python :: 3.9",
diff --git a/tox.ini b/tox.ini
index d234dcd1f..99a6dff73 100644
--- a/tox.ini
+++ b/tox.ini
@@ -1,6 +1,6 @@
 [tox]
 envlist =
-    py{36,37,38,39,310}-{local,integ,accept,examples}, nocmk,
+    py{37,38,39,310}-{local,integ,accept,examples}, nocmk,
     bandit, doc8, readme, docs,
     {flake8,pylint}{,-tests,-examples},
     isort-check, black-check,