diff --git a/kotlinx-coroutines-core/jvm/resources/META-INF/proguard/coroutines.pro b/kotlinx-coroutines-core/jvm/resources/META-INF/proguard/coroutines.pro
index d69e573c2e..60c8d61243 100644
--- a/kotlinx-coroutines-core/jvm/resources/META-INF/proguard/coroutines.pro
+++ b/kotlinx-coroutines-core/jvm/resources/META-INF/proguard/coroutines.pro
@@ -12,3 +12,9 @@
     volatile <fields>;
 }
 
+# These classes are only required by kotlinx.coroutines.debug.AgentPremain, which is only loaded when
+# kotlinx-coroutines-core is used as a Java agent, so these are not needed in contexts where ProGuard is used.
+-dontwarn java.lang.instrument.ClassFileTransformer
+-dontwarn sun.misc.SignalHandler
+-dontwarn java.lang.instrument.Instrumentation
+-dontwarn sun.misc.Signal